Improved arachidonic acids production from the fungus Mortierella alpina by glutamate supplementation

被引:23
作者
Yu, LJ [1 ]
Qin, WM [1 ]
Lan, WZ [1 ]
Zhou, PP [1 ]
Zhu, M [1 ]
机构
[1] Huazhong Univ Sci & Technol, Sch Life Sci & Technol, Wuhan 430074, Hubei, Peoples R China
关键词
arachidonic acid; glutamate; Mortierella alpina;
D O I
10.1016/S0960-8524(02)00312-7
中图分类号
S2 [农业工程];
学科分类号
0828 ;
摘要
The effect of various concentrations of glutamate on arachidonic acid (AA) production from Mortierella alpina in shaker flask culture was studied. Glutamate supplementation promoted Mortierella growth, accelerated substrate metabolism, and increased AA production, and a concentration of 0.8 g/l glutamate resulted in the greatest AA yield (1.41 g/l). In 10 1 airlift stirred fermenter culture, AA yield in the cultures exposed to 0.8 g/1 glutamate was also greater than that in the control (0.56 g/l). (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:265 / 268
页数:4
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