Air pollution and multiple sclerosis: a comprehensive review

被引：24

作者：

Abbaszadeh, Sahand ^{[1
]}

Tabary, Mohammadreza ^{[2
]}

Aryannejad, Armin ^{[2
]}

Abolhasani, Ruhollah ^{[3
]}

Araghi, Farnaz ^{[4
]}

Khaheshi, Isa ^{[5
]}

Azimi, Amirreza ^{[6
]}

机构：

[1] Arak Univ Med Sci, Sch Med, Students Res Comm, Arak, Iran

[2] Univ Tehran Med Sci, Expt Med Res Ctr, Tehran 13145784, Iran

[3] Univ Tehran Med Sci, Sch Med, Tehran, Iran

[4] Shahid Beheshti Univ Med Sci, Skin Res Ctr, Tehran, Iran

[5] Shahid Beheshti Univ Med Sci, Cardiovasc Res Ctr, Tehran, Iran

[6] Univ Tehran Med Sci, Multiple Sclerosis Res Ctr, Neurosci Inst, Tehran, Iran

来源：

NEUROLOGICAL SCIENCES | 2021年 / 42卷 / 10期

关键词：

Multiple sclerosis; Air pollution; Central nervous system; Particulate matter; Gaseous pollutant; PARTICULATE MATTER; ULTRAFINE PARTICLES; POTENTIAL IMPACT; RISK-FACTOR; EXPOSURE; DISEASE; QUALITY; COARSE; HEALTH; TOXICITY;

D O I：

10.1007/s10072-021-05508-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Multiple sclerosis (MS) is an inflammatory, autoimmune demyelinating disorder of the central nervous system (CNS), leading to progressive functional impairments, and many intrinsic and acquired factors are believed to be associated with its development and relapse. In terms of environmental factors, air pollution has gained much attention during recent decades, as chronic exposure to ambient air pollution seems to increase the level of some pro-inflammatory markers in the human brain, which can lead to neuroinflammation, neurodegeneration, and blood-brain barrier (BBB) breakdown. These events may also be associated with the risk of MS development and relapse. In this review, we aimed to summarize recent findings around the impact of air pollutants, including particulate matter (PM10, PM2.5, and ultra-fine particles), gaseous pollutants (carbon monoxide [CO], nitrogen oxides [NOx], sulfur dioxide [SO2], and ozone [O-3]), and heavy metals, on MS development and relapse.

引用

页码：4063 / 4072

页数：10

共 74 条

[1] The relationship of indoor radon gas concentration with multiple sclerosis: a case-control study [J].

Abaszadeh Fathabadi, Zeynab ;

Ehrampoush, Mohamad Hassan ;

Mirzaei, Masuod ;

Mokhtari, Mehdi ;

Nadi Sakhvidi, Mohamad ;

Rahimdel, Abolghasem ;

Dehghani Tafti, Arefeh ;

Fallah Yakhdani, Monire ;

Atefi, Atefe ;

Eslami, Hadi ;

Ebrahimi, Ali Asghar .

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2020, 27 (14) :16350-16361

[2] Correlation between heavy metal exposure and GSTM1 polymorphism in Iranian multiple sclerosis patients [J].

Aliomrani, Mehdi ;

Sahraian, Mohammad A. ;

Shirkhanloo, Hamid ;

Sharifzadeh, Mohammad ;

Khoshayand, Mohammad R. ;

Ghahremani, Mohammad H. .

NEUROLOGICAL SCIENCES, 2017, 38 (07) :1271-1278

[3]

Aliomrani M, 2016, IRAN J PHARM RES, V15, P825

[4] Multiple sclerosis in Canada 2011 to 2031: results of a microsimulation modelling study of epidemiological and economic impacts [J].

Amankwah, Nana ;

Marrie, Ruth Ann ;

Bancej, Christina ;

Garner, Rochelle ;

Manuel, Douglas G. ;

Wall, Ron ;

Fines, Philippe ;

Bernier, Julie ;

Tu, Karen ;

Reimer, Kim .

HEALTH PROMOTION AND CHRONIC DISEASE PREVENTION IN CANADA-RESEARCH POLICY AND PRACTICE, 2017, 37 (02) :37-48

[5] Effects of particulate matter exposure on multiple sclerosis hospital admission in Lombardy region, Italy [J].

Angelici, Laura ;

Piola, Mirko ;

Cavalleri, Tommaso ;

Randi, Giorgia ;

Cortini, Francesca ;

Bergamaschi, Roberto ;

Baccarelli, Andrea A. ;

Bertazzi, Pier Alberto ;

Pesatori, Angela Cecilia ;

Bollati, Valentina .

ENVIRONMENTAL RESEARCH, 2016, 145 :68-73

[6] Stress as a Risk Factor for Multiple Sclerosis Onset or Relapse: A Systematic Review [J].

Artemiadis, Artemios K. ;

Anagnostouli, Maria C. ;

Alexopoulos, Evangelos C. .

NEUROEPIDEMIOLOGY, 2011, 36 (02) :109-120

[7] An 8-year study of people with multiple sclerosis in Isfahan, Iran: Association between environmental air pollutants and severity of disease [J].

Ashtari, Fereshte ;

Esmaeil, Nafiseh ;

Mansourian, Marjan ;

Poursafa, Parinaz ;

Mirmosayyeb, Omid ;

Barzegar, Mandi ;

Pourgheisari, Hajar .

JOURNAL OF NEUROIMMUNOLOGY, 2018, 319 :106-111

[8] Long-term exposure to air pollution and the incidence of multiple sclerosis: A population-based cohort study [J].

Bai, Li ;

Burnett, Richard T. ;

Kwong, Jeffrey C. ;

Hystad, Perry ;

van Donkelaar, Aaron ;

Brook, Jeffrey R. ;

Tu, Karen ;

Copes, Ray ;

Goldberg, Mark S. ;

Martin, Randall, V ;

Murray, Brian J. ;

Kopp, Alexander ;

Chen, Hong .

ENVIRONMENTAL RESEARCH, 2018, 166 :437-443

[9] PM2.5 exposure as a risk factor for multiple sclerosis. An ecological study with a Bayesian mapping approach [J].

Bergamaschi, Roberto ;

Monti, Maria Cristina ;

Trivelli, Leonardo ;

Mallucci, Giulia ;

Gerosa, Leonardo ;

Pisoni, Enrico ;

Montomoli, Cristina .

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2021, 28 (03) :2804-2809

[10] Air pollution is associated to the multiple sclerosis inflammatory activity as measured by brain MRI [J].

Bergamaschi, Roberto ;

Cortese, Andrea ;

Pichiecchio, Anna ;

Berzolari, Francesca Gigli ;

Borrelli, Paola ;

Mallucci, Giulia ;

Bollati, Valentina ;

Romani, Alfredo ;

Nosari, Guido ;

Villa, Silvia ;

Montomoli, Cristina .

MULTIPLE SCLEROSIS JOURNAL, 2018, 24 (12) :1578-1584

← 1 2 3 4 5 6 7 8 →