Self-exploding capsules

被引:17
作者
De Geest, Bruno G. [1 ]
De Koker, Stefaan [2 ]
Demeester, Jo [3 ]
De Smedt, Stefaan C. [3 ]
Hennink, Wim E. [4 ]
机构
[1] Univ Ghent, Pharmaceut Technol Lab, Dept Pharmaceut, B-9000 Ghent, Belgium
[2] Univ Ghent, Lab Mol Immunol, Dept Mol Biomed Res, B-9000 Ghent, Belgium
[3] Univ Ghent, Dept Pharmaceut, Lab Gen Biochem & Phys Pharm, B-9000 Ghent, Belgium
[4] Univ Utrecht, Dept Pharmaceut, Utrecht, Netherlands
关键词
ULTRATHIN MULTILAYER FILMS; DEXTRAN-BASED HYDROGELS; CATIONIC BIPOLAR AMPHIPHILES; POLYELECTROLYTE MICROCAPSULES; DRUG-DELIVERY; CONTROLLED-RELEASE; CHARGED SURFACES; ASSEMBLY PROCESS; LIPID-BILAYERS; MACROMOLECULE ENCAPSULATION;
D O I
10.1039/b9py00287a
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Self-exploding microcapsules are core-shell capsules that consist of a degradable microgel core surrounded by a semi-permeable membrane. When the microgel core degrades, the swelling pressure increases and finally the rupture of the surrounding membrane leads to release of the encapsulated species. This type of capsule could find applications in fields such as e.g. drug delivery, tissue
引用
收藏
页码:137 / 148
页数:12
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