Self-exploding capsules

被引:17
作者
De Geest, Bruno G. [1 ]
De Koker, Stefaan [2 ]
Demeester, Jo [3 ]
De Smedt, Stefaan C. [3 ]
Hennink, Wim E. [4 ]
机构
[1] Univ Ghent, Pharmaceut Technol Lab, Dept Pharmaceut, B-9000 Ghent, Belgium
[2] Univ Ghent, Lab Mol Immunol, Dept Mol Biomed Res, B-9000 Ghent, Belgium
[3] Univ Ghent, Dept Pharmaceut, Lab Gen Biochem & Phys Pharm, B-9000 Ghent, Belgium
[4] Univ Utrecht, Dept Pharmaceut, Utrecht, Netherlands
关键词
ULTRATHIN MULTILAYER FILMS; DEXTRAN-BASED HYDROGELS; CATIONIC BIPOLAR AMPHIPHILES; POLYELECTROLYTE MICROCAPSULES; DRUG-DELIVERY; CONTROLLED-RELEASE; CHARGED SURFACES; ASSEMBLY PROCESS; LIPID-BILAYERS; MACROMOLECULE ENCAPSULATION;
D O I
10.1039/b9py00287a
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Self-exploding microcapsules are core-shell capsules that consist of a degradable microgel core surrounded by a semi-permeable membrane. When the microgel core degrades, the swelling pressure increases and finally the rupture of the surrounding membrane leads to release of the encapsulated species. This type of capsule could find applications in fields such as e.g. drug delivery, tissue
引用
收藏
页码:137 / 148
页数:12
相关论文
共 75 条
  • [1] Polyelectrolyte multilayer capsule permeability control
    Antipov, AA
    Sukhorukov, GB
    Leporatti, S
    Radtchenko, IL
    Donath, E
    Möhwald, H
    [J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2002, 198 : 535 - 541
  • [2] Polyelectrolyte multilayer capsules as vehicles with tunable permeability
    Antipov, AA
    Sukhorukov, GB
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2004, 111 (1-2) : 49 - 61
  • [3] Polymeric microcapsules with light responsive properties for encapsulation and release
    Bedard, Matthieu F.
    De Geest, Bruno G.
    Skirtach, Andre G.
    Moehwald, Helmuth
    Sukhorukov, Gleb B.
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2010, 158 (1-2) : 2 - 14
  • [4] Direction specific release from giant microgel-templated polyelectrolyte microcontainers
    Bedard, Matthieu F.
    De Geest, Bruno G.
    Moehwald, Helmuth
    Sukhorukov, Gleb B.
    Skirtach, Andre G.
    [J]. SOFT MATTER, 2009, 5 (20) : 3927 - 3931
  • [5] A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts
    Birkett, A
    Lyons, K
    Schmidt, A
    Boyd, D
    Oliveira, GA
    Siddique, A
    Nussenzweig, R
    Calvo-Calle, JM
    Nardin, E
    [J]. INFECTION AND IMMUNITY, 2002, 70 (12) : 6860 - 6870
  • [6] Engineering lipobeads: Properties of the hydrogel core and the lipid bilayer shell
    Buck, S
    Pennefather, PS
    Xue, HY
    Grant, J
    Cheng, YL
    Allen, CJ
    [J]. BIOMACROMOLECULES, 2004, 5 (06) : 2230 - 2237
  • [7] Cadée JA, 2000, J BIOMED MATER RES, V50, P397
  • [8] Release of recombinant human interleukin-2 from dextran-based hydrogels
    Cadée, JA
    de Groot, CJ
    Jiskoot, W
    den Otter, W
    Hennink, WE
    [J]. JOURNAL OF CONTROLLED RELEASE, 2002, 78 (1-3) : 1 - 13
  • [9] Nanoengineering of inorganic and hybrid hollow spheres by colloidal templating
    Caruso, F
    Caruso, RA
    Möhwald, H
    [J]. SCIENCE, 1998, 282 (5391) : 1111 - 1114
  • [10] Layer-by-layer coating of degradable microgels for pulsed drug delivery
    De Geest, B. G.
    Dejugnat, C.
    Verhoeven, E.
    Sukhorukov, G. B.
    Jonas, A. M.
    Plain, J.
    Demeester, J.
    De Smedt, S. C.
    [J]. JOURNAL OF CONTROLLED RELEASE, 2006, 116 (02) : 159 - 169