Nickel-Catalyzed Reductive Cross-Coupling of Aryl Triflates and Nonaflates with Alkyl Iodides

被引：11

作者：

Sumida, Yuto ^{[1
]}

Sumida, Tomoe ^{[1
]}

Hosoya, Takamitsu ^{[1
,2
]}

机构：

[1] RIKEN, Ctr Life Sci Technol, Div Biofunct Dynam Imaging, Chem Biol Team,Chuo Ku, 6-7-3 Minatojima Minamimachi, Kobe, Hyogo 6500047, Japan

[2] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Lab Chem Biosci, Chiyoda Ku, 2-3-10 Kanda Surugadai, Tokyo 1010062, Japan

来源：

SYNTHESIS-STUTTGART | 2017年 / 49卷 / 16期

关键词：

reductive alkylation; cross-electrophile coupling; nickel catalysis; aryl triflate; alkyl iodide; aromatic compounds; HETEROARYL BROMIDES; FACILE SYNTHESIS; ORGANIC HALIDES; BOND-CLEAVAGE; N-ARYLATION; ARYNES; COMPLEXES; BIS(PINACOLATO)DIBORON; ELECTROPHILES; BORYLATION;

D O I：

10.1055/s-0036-1588464

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A nickel-catalyzed cross-electrophile coupling of aryl triflates and nonaflates with alkyl iodides using manganese(0) as a reductant is described. The method is applicable to the reductive alkylation of various aryl sulfonates, including o-borylaryl triflate, which enabled efficient construction of diverse alkylated arenes under mild conditions.

引用

页码：3590 / 3601

页数：12

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