Penicillin acylase catalysis in the presence of ionic liquids

被引：20

作者：

Zhang, Wei-Guo ^{[1
]}

Wei, Dong-Zhi ^{[1
]}

Yang, Xue-Peng ^{[1
]}

Song, Qing-Xun ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Inst New World Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

来源：

BIOPROCESS AND BIOSYSTEMS ENGINEERING | 2006年 / 29卷 / 5-6期

关键词：

ionic liquids; penicillin acylase; enzyme stability;

D O I：

10.1007/s00449-006-0085-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Several ionic liquids were used as reaction media for penicillin G acylase catalysis. In all the assayed ionic liquids, [bmim]PF6 proved good media for PGA-catalyzed hydrolysis. A novel [bmim]PF6/water two-phase system is provided for 6-aminopenicillanic acid (APA) production, which will be more benefical than aquous batch systems used widely in industrial production of APA.

引用

页码：379 / 383

页数：5

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