Thalidomide inhibits the growth and progression of hepatic epithelioid hemangioendothelioma

被引：50

作者：

Mascarenhas, RCV

Sanghvi, AN

Friedlander, L

Geyer, SJ

Beasley, HS

Van Thiel, DH

机构：

[1] Loyola Univ, Med Ctr, Stritch Sch Med, Dept Med, Maywood, IL 60153 USA

[2] Temple Univ, Western Penn Hosp, Dept Radiol, Pittsburgh, PA USA

[3] Temple Univ, Western Penn Hosp, Dept Pathol, Pittsburgh, PA USA

[4] Temple Univ, Western Penn Hosp, Dept Hepatol, Pittsburgh, PA USA

来源：

ONCOLOGY | 2004年 / 67卷 / 5-6期

关键词：

thalidomide; epithelioid hemangioendothelioma; angiogenic inhibition; vascular tumor;

D O I：

10.1159/000082932

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hepatic epithelioid hemangioendothelioma (HEH) is a rare vascular tumor of the liver with an unpredictable malignant potential. Its growth can lead to hepatic failure, extrahepatic metastasis and death. Surgical resection or liver transplantation is the treatment of choice if metastasis is not identified. Several antineoplastic agents have been proposed for cases of nonresectable HEH. We report the case of a 52-year-old patient with HEH metastatic to the lungs who was successfully treated with oral thalidomide therapy. Copyright (C) 2004 S. Karger AG, Basel.

引用

页码：471 / 475

页数：5

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