The Role of Geometric Parameters in the Prediction of Abdominal Aortic Aneurysm Wall Stress

被引:83
作者
Georgakarakos, E. [1 ]
Ioannou, C. V. [1 ]
Kamarianakis, Y. [2 ]
Papaharilaou, Y.
Kostas, T. [1 ]
Manousaki, E. [3 ]
Katsamouris, A. N. [1 ]
机构
[1] Univ Crete, Sch Med, Dept Vasc Surg, Iraklion, Greece
[2] Cornell Univ, Dept Civil & Environm Engn, Ithaca, NY 14853 USA
[3] Univ Crete, Sch Med, Dept Radiol, Iraklion, Greece
关键词
Wall stress; Intraluminal thrombus; Finite element analysis; Centreline geometry; INTRALUMINAL THROMBUS; RUPTURE; RISK; MODELS;
D O I
10.1016/j.ejvs.2009.09.026
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: To study the correlation between peak watt stress (PWS) and abdominal aorta aneurysm (AAA) geometric parameters in the presence of intraluminal thrombus (ILT). Design: Computational study using finite element analysis. Material: AAA models were created by three-dimensional (3D) reconstruction of in vivo acquired computed tomography (CT) images from 19 patients. Methods: PWS was evaluated in the presence and absence of ILT. Delta PWS% represents the percentage change in PWS in the presence of ILT. The 3D lumen centrelines were extracted, and the values of torsion, tortuosity and mean curvature were estimated. Results: A positive correlation was observed between Delta PWS% and relative ILT volume (P = 0.03). PWS in the presence of ILT significantly correlated only with the degree of centerline tortuosity (P = 0.003) and maximum diameter (P < 0.0001). The optimal predictive model for PWS in the presence of ILT was estimated to contain both maximum diameter and centreline tortuosity. Conclusions: Specific geometric parameters in AAA models in the presence of ILT could serve as potential predictors of elevated PWS. PWS correlated significantly with the maximum diameter and the degree of centreline tortuosity. Centreline tortuosity may become a useful addition to maximum diameter in the decision-making process of AAA treatment. (C) 2009 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:42 / 48
页数:7
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