"Atypical Steroid Response" in a Pulmonary Inflammatory Myofibroblastic Tumor

被引：8

作者：

Sacco, Oliviero ^{[1
]}

Gambini, Claudio ^{[2
]}

Gardella, Chiara ^{[1
]}

Toma, Paolo ^{[3
]}

Rossi, Umberto G. ^{[4
]}

Jasonni, Vincenzo ^{[5
]}

Bush, Andrew ^{[6
]}

Rossi, Giovanni A. ^{[1
]}

机构：

[1] Giannina Gaslini Res Inst, Pediat Pulm & Allergol Unit, Genoa, Italy

[2] Giannina Gaslini Res Inst, Pathol Unit, Genoa, Italy

[3] Giannina Gaslini Res Inst, Radiol Unit, Genoa, Italy

[4] San Martino Univ Hosp, Dept Diagnost & Intervent Radiol, Genoa, Italy

[5] Giannina Gaslini Res Inst, Pediat Surg Unit, Genoa, Italy

[6] Royal Brompton Hosp, Dept Paediat Respirol, London SW3 6LY, England

来源：

PEDIATRIC PULMONOLOGY | 2010年 / 45卷 / 07期

关键词：

inflammatory myofibroblastic tumor; plasma cell granuloma; atelectasis; mediastinal mass; PLASMA-CELL GRANULOMA; SOFT-TISSUE; PSEUDOTUMOR; LUNG; CHILDREN; PROGNOSIS; EXPRESSION; DIAGNOSIS; SARCOMA; ALK1;

D O I：

10.1002/ppul.21237

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A 6-year-old girl was evaluated for the presence of a paratracheal mass with right upper lobe atelectasis due to an endobronchial mass. Bronchoscopic biopsy established a diagnosis of inflammatory myofibroblastic tumor (IMT) and prednisone initially led to a significant reduction of the endobronchial lesion. However, 8 weeks later, when still on prednisone, the mediastinal mass enlarged dramatically. At thoracotomy, a well-circumscribed, multilobulated mass was partially resected and a diagnosis of IMT confirmed. Immunosuppression by corticosteroids may have favored the rapid progression of this apparently benign, indolent tumor. Pediatr Pulmonol. 2010; 45:721-726. (C) 2010 Wiley-Liss, Inc.

引用

页码：721 / 726

页数：6

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