Cognitive functioning in aging and dementia:: The Kungsholmen Project

被引:40
作者
Bäckman, L
Wahlin, Å
Small, BJ
Herlitz, A
Winblad, B
Fratiglioni, L
机构
[1] Karolinska Inst, NEUROTEC, Div Geriatr Epidemiol, Aging Res Ctr, S-11382 Stockholm, Sweden
[2] Stockholm Gerontol Res Ctr, Stockholm, Sweden
[3] Stockholm Univ, Dept Psychol, S-10691 Stockholm, Sweden
[4] Univ S Florida, Dept Gerontol, Tampa, FL USA
关键词
D O I
10.1080/13825580490511099
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The Kungsholmen Project (KP) is a community-based longitudinal study of aging and dementia targeting the 75+ population. In this article, we review empirical studies with a cognitive focus from the KP. The main findings indicate that (a) there is an age-related decline for some cognitive domains (e.g., episodic memory, verbal fluency, visuoconstructive skill, psychomotor speed), but not for others (e.g., primary memory, visuoperceptive skill, motor-hand coordination), (b) multiple individual-difference variables within demographic (e.g., sex, education) life-style (e.g., activity levels), genetic (e.g., apolipoprotein E genotype), and health-related (e.g., vitamin B deficiency, depression, diabetes) domains are related to late-life cognitive functioning, (c) a potential for improving cognitive performance - a reserve capacity - is present also among very old adults, (d) the 2 most common dementia diseases, Alzheimer's disease (AD) and vascular dementia (VaD), affect cognition in a strikingly similar manner, (e) the role of individual-difference variables in cognitive functioning is markedly reduced in dementia - the pathogenesis itself may overshadow the influence of other variables, and (f) there is a long preclinical period in dementia during which cognitive deficits are detectable. As is true with the other projects represented in this issue, the KP portrays a rather diversified picture of cognitive aging, although systematic patterns are evident with regard to the variability of late-life cognitive functioning.
引用
收藏
页码:212 / 244
页数:33
相关论文
共 145 条
[1]   Preclinical prediction of AD using neuropsychological tests [J].
Albert, MS ;
Moss, MB ;
Tanzi, R ;
Jones, K .
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY, 2001, 7 (05) :631-639
[2]   Cognitive support at episodic encoding and retrieval:: Similar patterns of utilization in community-based samples of Alzheimer's disease and vascular dementia patients [J].
Almkvist, O ;
Fratiglioni, L ;
Agüero-Torres, H ;
Viitanen, M ;
Bäckman, L .
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 1999, 21 (06) :816-830
[3]  
[Anonymous], 2001, Handbook of neuropsychology
[4]  
[Anonymous], 1996, COGNITIVE NEUROPSYCH
[5]  
Backman L, 1998, PSYCHOL AGING, V13, P267
[6]   COMPENSATION AND RECODING - A FRAMEWORK FOR AGING AND MEMORY RESEARCH [J].
BACKMAN, L .
SCANDINAVIAN JOURNAL OF PSYCHOLOGY, 1985, 26 (03) :193-207
[7]   Rate of cognitive decline in preclinical Alzheimer's disease:: The role of comorbidity [J].
Bäckman, L ;
Jones, S ;
Small, BJ ;
Agüero-Torres, H ;
Fratiglioni, L .
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES, 2003, 58 (04) :P228-P236
[8]   The influence of depressive symptomatology on episodic memory functioning among clinically nondepressed older adults [J].
Backman, L ;
Hill, RD ;
Forsell, Y .
JOURNAL OF ABNORMAL PSYCHOLOGY, 1996, 105 (01) :97-105
[9]  
Backman L, 1996, PSYCHOL AGING, V11, P649
[10]   Influences of preclinical dementia and impending death on the magnitude of age-related cognitive deficits [J].
Bäckman, L ;
Laukka, EJ ;
Wahlin, Å ;
Small, BJ ;
Fratiglioni, L .
PSYCHOLOGY AND AGING, 2002, 17 (03) :435-442