Molecular genetics of melanocytic neoplasia: practical applications for diagnosis

被引：19

作者：

Bastian, BC

机构：

[1] Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USA

来源：

PATHOLOGY | 2004年 / 36卷 / 05期

关键词：

melanoma; melanocytic nevus; melanocytic naevus; genetics; pathology; chromosomes;

D O I：

10.1080/00303020412331282717

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Pathology is the gold standard for the diagnosis of skin cancer. However, despite morphological criteria that have been constantly refined, there remain areas in which histopathological analysis does not permit an unequivocal diagnosis. Among these, problems most frequently arise with melanocytic lesions. This article reviews recent molecular studies that have revealed differences in the pattern of chromosomal aberrations between naevi and melanoma that could become relevant as adjunctive diagnostic methods in the future.

引用

页码：458 / 461

页数：4

共 28 条

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