Cognate chemokine receptor 1 messenger ribonucleic acid expression in peripheral blood as a diagnostic test for endometriosis

被引:24
作者
Agic, Admir
Xu, Hong
Rehbein, Mirka
Wolfler, Monika M.
Ebert, Andreas D.
Hornung, Daniela
机构
[1] Univ Schleswig Holstein, Dept Obstet & Gynecol, D-23538 Lubeck, Germany
[2] Zhejiang Univ, Womens Hosp, Sch Med, Hangzhou 310027, Peoples R China
[3] Dept Obstet & Gynecol, Aachen, Germany
[4] Vivantes Humboldt Klinikum, Dept Obstet & Gynecol, Berlin, Germany
关键词
D O I
10.1016/j.fertnstert.2006.09.012
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
We investigated the expression of the cognate chemokine receptor 1 (CCR1) messenger ribonucleic acid,a, G-protein-coupled cognate chemokine receptor with high affinity for RANTES (Regulated upon Activation, Normal T cells Expressed and Secreted), in peripheral blood leukocytes of women with and without endometriosis, and its potential use as a diagnostic test for endometriosis. Because patients with an earlier diagnosis of this disease have a better treatment outcome and a reduced recurrence rate, CCR1 mRNA measurement in the peripheral blood of patients with suspected endometriosis might give us a new perspective in diagnosing and treating this disease earlier and better.
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收藏
页码:982 / 984
页数:3
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