Semiconductor Nanorod-Carbon Nanotube Biomimetic Films for Wire-Free Photostimulation of Blind Retinas

被引：98

作者：

Bareket, Lilach ^{[1
,2
]}

Waiskopf, Nir ^{[4
,5
]}

Rand, David ^{[1
,2
]}

Lubin, Gur ^{[1
,2
]}

David-Pur, Moshe ^{[1
,2
]}

Ben-Dov, Jacob ^{[1
,2
]}

Roy, Soumyendu ^{[1
,2
]}

Eleftheriou, Cyril ^{[6
]}

Sernagor, Evelyne ^{[6
]}

Cheshnovsky, Ori ^{[2
,3
]}

Banin, Uri ^{[4
,5
]}

Hanein, Yael ^{[1
,2
]}

机构：

[1] Tel Aviv Univ, Sch Elect Engn, IL-69978 Tel Aviv, Israel

[2] Tel Aviv Univ, Ctr Nanosci & Nanotechnol, IL-69978 Tel Aviv, Israel

[3] Tel Aviv Univ, Sch Chem, IL-69978 Tel Aviv, Israel

[4] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

[5] Hebrew Univ Jerusalem, Ctr Nanosci & Nanotechnol, IL-91904 Jerusalem, Israel

[6] Newcastle Univ, Fac Med Sci, Inst Neurosci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

来源：

NANO LETTERS | 2014年 / 14卷 / 11期

基金：

欧洲研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

Neural photostimulation; carbon nanotubes; quantum rods; retinal implant; neural prosthesis; plasma polymerization; QUANTUM DOTS; MULTIELECTRODE ARRAY; BRAIN-STIMULATION; CHARGE-TRANSFER; LIGHT; CHICK; INTERFACE; CELLS; EXPRESSION; SYSTEM;

D O I：

10.1021/nl5034304

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the development of a semiconductor nanorod-carbon nanotube based platform for wire-free, light induced retina stimulation. A plasma polymerized acrylic acid midlayer was used to achieve covalent conjugation of semiconductor nanorods directly onto neuro-adhesive, three-dimensional carbon nanotube surfaces. Photocurrent, photovoltage, and fluorescence lifetime measurements validate efficient charge transfer between the nanorods and the carbon nanotube films. Successful stimulation of a light-insensitive chick retina suggests the potential use of this novel platform in future artificial retina applications.

引用

页码：6685 / 6692

页数：8

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