New 4,4-difluoro-3a,4a-diaza-s-indacene (BODIPY)-labeled sphingolipids for membrane studies

被引:4
作者
Boldyrev, I. A. [1 ]
Molotkovsky, J. G. [1 ]
机构
[1] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
基金
俄罗斯基础研究基金会;
关键词
fluorescent lipid probes; BODIPY; synthesis; membrane studies; PROBES;
D O I
10.1134/S1068162010040096
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The synthesis of a series of new fluorescently labeled sphingolipids containing a 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl (Me(4)-BODIPY-8) group at the omega-position of a fatty acyl residue is described. The obtained probes were used in studies of biological and model membrane systems.
引用
收藏
页码:508 / 511
页数:4
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