Application of near-infrared spectroscopy to investigate brain activity: Clinical research

被引：4

作者：

Lichty, W ^{[1
]}

Sakatania, K ^{[1
]}

Xie, YX ^{[1
]}

Zuo, HC ^{[1
]}

机构：

[1] Tsing Hua Univ, Sino Japanese Friendship Hosp, Inst Med Sci, Beijing 100084, Peoples R China

来源：

OPTICAL SENSING, IMAGING, AND MANIPULATION FOR BIOLOGICAL AND BIOMEDICAL APPLICATIONS | 2000年 / 4082卷

关键词：

near-infrared spectroscopy; brain activation; cognition; language; cerebral blood flow;

D O I：

10.1117/12.390548

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Near infrared spectroscopy has recently been used to measure changes of optical parameters (i.e., light absorption or scattering) of brain tissue. The fact that the equipment is generally compact, portable, noninvasive, and reasonably priced makes it ideal for clinical and nonclinical evaluation and monitoring of brain function Clinical and nonclinical studies evaluating changes related to light absorption are discussed, with an emphasis on cerebral blood oxygenation (CBO) changes and hemodynamic responses while performing cognitive tasks. With respect to the clinical studies, the focus is on variations in patterns of oxygenated hemoglobin (Oxy-Hb), deoxygenated hemoglobin (Deoxy-Hb) and Total-Hb (sum of Oxy-Hb and Deoxy-Hb). The studies about clinical applications includes research we have conducted with older adults and aphasics. Implications regarding the use of MRS for clinical purposes are considered.

引用

页码：34 / 39

页数：6

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