2-amidinylindole-3-carbaldehydes:: Synthesis of new tetracyclic compounds containing the pyrrolo[1,2-c]1,4-diazepine ring

被引：9

作者：

Clerici, F

Erba, E

Pocar, D

机构：

[1] Univ Milan, Ist Chim Organ Alessandro, I-20133 Milan, Italy

[2] Univ Milan, Ctr Interuniv Ricerca Reaz Pericicliche, I-20133 Milan, Italy

[3] Univ Milan, Sintesi Sistemi Etero & Carbociclici, I-20133 Milan, Italy

来源：

TETRAHEDRON | 2003年 / 59卷 / 10期

关键词：

amidines; anthramycin; pyrrolo[1,2-c]-1,4-diazepine; intramolecular cyclization;

D O I：

10.1016/S0040-4020(03)00146-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Amidinylindol-3-carbaldehydes bearing an alpha-alkoxycarbonyl substituent on the cyclic-tertiary amine moiety were prepared. Pyrolysis of these amidines in diethylenglycol-monoethyl ether produced mainly a pyrrolo[ 1',2'-1,2]-1,4-diazepino[5,6-b]indol-7,11-dione. A similar result was obtained starting from 2-amidinylbenzofuran-3-carbaldehyde. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1667 / 1671

页数：5

共 8 条

[1]

BECHER J, 1989, SYNTHESIS-STUTTGART, P530

[2] 2-Amidinylindole-3-carbaldehydes:: Versatile synthons for the preparation of α-carboline derivatives [J].