Malignant odontogenic myxoma of the maxilla: case with cytogenetic confirmation

被引:1
作者
Pahl, S [1 ]
Henn, W
Binger, T
Stein, U
Remberger, K
机构
[1] Univ Saarlandes, Inst Pathol, Dept Pathol, D-66421 Homburg, Germany
[2] Univ Saarlandes, Dept Human Genet, D-66421 Homburg, Germany
[3] Univ Saarlandes, Dept Oral & Maxillofacial Surg, D-66421 Homburg, Germany
关键词
maxillary sinus neoplasms; myxoma; odontogenic tumors;
D O I
暂无
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
An odontogenic myxoma of the maxilla with an aggressive clinical course is presented. The tumour arose in a 53-year-old patient, recurred two times after extended maxillectomy and ultimately caused the patient's death by uncontrollable local disease with infiltration of the cranial cavity. Microscopically, the tumour showed histological features of a low grade malignant myxosarcoma with cellular areas, enhanced mitotic activity and nuclear pleomorphism. Cytogenetic analysis revealed an unexpectedly aberrant hypertetraploid chromosome complement, that was considered as incompatible with the usual karyotypic patterns of benign tumours.
引用
收藏
页码:533 / 535
页数:3
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