Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment

被引:33
作者
Akhbarizadeh, Razegheh [1 ,2 ]
Russo, Giacomo [3 ,4 ]
Rossi, Sergio [6 ]
Golianova, Katarina [7 ]
Moore, Farid [9 ]
Guida, Marco [8 ]
De Falco, Maria [8 ]
Grumetto, Lucia [3 ,5 ]
机构
[1] Bushehr Univ Med Sci, Syst Environm Hlth & Energy Res Ctr, Persian Gulf Biomed Sci Res Inst, Bushehr, Iran
[2] Bushehr Univ Med Sci, Persian Gulf Marine Biotechnol Res Ctr, Persian Gulf Biomed Sci Res Inst, Bushehr, Iran
[3] Univ Naples Federico II, Sch Med & Surg, Dept Pharm, Pharm Anal & Biopharm Lab, Via D Montesano 49, I-80131 Naples, Italy
[4] Edinburgh Napier Univ, Sch Appl Sci, Sighthill Campus,9 Sighthill Ct, Edinburgh EH11 4BN, Midlothian, Scotland
[5] Consorzio Interuniv INBB, Viale Medaglie Oro 305, I-00136 Rome, Italy
[6] CNR, Inst Genet & Biophys ABT, Via Pietro Castellino 111, I-80131 Naples, Italy
[7] Safarik Univ, Dept Biophys, Jesenna 5, Kosice 04154, Slovakia
[8] Univ Federico II Naples, Dept Biol, Naples, Italy
[9] Shiraz Univ, Coll Sci, Dept Earth Sci, Shiraz 71454, Iran
关键词
Endocrine disruptors; Monte-Carlo simulation; Fish; Liver; Muscle; Persian gulf; PEARL RIVER ESTUARY; BISPHENOL-A; FRESH-WATER; METALS CONCENTRATIONS; MARINE-ENVIRONMENT; LAKE IMPLICATIONS; TRACE-METALS; ANALOGS; BIOACCUMULATION; CHEMICALS;
D O I
10.1016/j.marpolbul.2021.112241
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The occurrence of endocrine disrupting chemicals (EDCs) has been determined in two widely consumed fish species from Persian Gulf i.e., Epinephelus coioides and Platycephalus indicus by applying a validated analytical for the simultaneous detection of fourteen EDCs. The concentrations of all detected EDCs were greater in the liver than in the muscle (except for bisphenol A in P. indicus), suggesting a prolonged exposure of the fishes to these pollutants in the Persian Gulf. Specifically, the results showed that di (2-ethylhexyl) phthalate (DEHP) was the compound detected most frequently and at the highest concentration in both species. DEHP levels in ranged from 6.68 to 297.48 ?g g-dw? 1 and from 13.32 to 350.52 ?g g-dw? 1, in muscle and in liver, respectively. A risk assessment study was conducted, and demonstrated that consuming two fish based- meals per week may result in a moderate risk especially for vulnerable population groups.
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页数:10
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