Meroterpenoid MAPKAP (MK2) inhibitors isolated from the Indonesian marine sponge Acanthodendrilla sp

被引：27

作者：

Williams, DE

Telliez, JB

Liu, J

Tahir, A

van Soest, R

Andersen, RJ ^{[1
]}

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

[2] Univ British Columbia, Dept Earth & Ocean Sci, Vancouver, BC V6T 1Z1, Canada

[3] Wyeth Res, Oncol & Immunol Div, Pearl River, NY 10965 USA

[4] Univ Hasanuddin, Dept Marine Sci, Makassar 90245, Indonesia

[5] Univ Amsterdam, Zool Museum, NL-1090 AT Amsterdam, Netherlands

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 12期

关键词：

D O I：

10.1021/np049808d

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

(+)-Makassaric acid (1) and (+)-subersic acid (2), new meroterpenoid inhibitors of the protein kinase MK2, have been isolated from the marine sponge Acanthodendrilla sp. collected in Indonesia. The structures of (+)-makassaric acid (1) and (+)-subersic acid (2) were determined by spectroscopic analysis.

引用

页码：2127 / 2129

页数：3