Characterization of polyoxyalkylene block copolymers by combination of different chromatographic techniques and MALDI-TOF-MS

被引：26
作者：
Malik, Muhammad Imran [1 ,2 ]
Trathnigg, Bernd [1 ,2 ]
Bartl, Karin [2 ,3 ]
Saf, Robert [2 ,3 ]
机构：
[1] Karl Franzens Univ Graz, Inst Chem, A-8010 Graz, Austria
[2] Cent Polymer Labs CePoL, NAWI Graz, A-8010 Graz, Austria
[3] Graz Univ Technol, ICTM, A-8010 Graz, Austria
来源：
ANALYTICA CHIMICA ACTA | 2010年 / 658卷 / 02期
关键词：
Two dimensional chromatography (2D-LC); Liquid chromatography under critical conditions (LCCC); Matrix-assisted laser desorption ionization time-of-flight mass spectroscopy (MALDI-TOF-MS); Polyoxyalkylene block copolymers; SIZE-EXCLUSION CHROMATOGRAPHY; DESORPTION/IONIZATION MASS-SPECTROMETRY; POLYMER ELUTION CHROMATOGRAPHY; OXIDE) TRIBLOCK COPOLYMERS; REVERSE MICELLE FORMATION; PPO DIBLOCK COPOLYMERS; LIQUID-CHROMATOGRAPHY; PROPYLENE-OXIDE; AQUEOUS-SOLUTION; ETHYLENE-OXIDE;
D O I：
10.1016/j.aca.2009.11.017
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Polyoxyalkylene diblock copolymers (consisting of PEO as hydrophilic block and PBO or PHO as hydrophobic block) are characterized by combination of two dimensional liquid chromatography and MALDI-TOF-MS. Liquid chromatography under critical conditions (LCCC) is used as first dimension and fractions are collected, mobile phase evaporated and diluted in the mobile phase used in the second dimension (SEC, LCCC or LAC). This two-dimensional chromatography in combination of MALDI-TOF-MS gives information about purity of reaction products, presence of the by products, chemical composition and molar mass distribution of all the products. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：217 / 224
页数：8
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