Cell division

被引：241

作者：

Scholey, JM ^{[1
]}

Brust-Mascher, I ^{[1
]}

Mogilner, A ^{[1
]}

机构：

[1] Univ Calif Davis, Ctr Genet & Dev, Lab Cell & Computat Biol, Davis, CA 95616 USA

来源：

NATURE | 2003年 / 422卷 / 6933期

关键词：

D O I：

10.1038/nature01599

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In creating the mitotic spindle and the contractile ring, natural selection has engineered fascinating precision machines whose movements depend upon forces generated by ensembles of cytoskeletal proteins. These machines segregate chromosomes and divide the cell with high fidelity. Current research on the mechanisms and regulation of spindle morphogenesis, chromosome motility and cytokinesis emphasizes how ensembles of dynamic cytoskeletal polymers and multiple motors cooperate to generate the forces that guide the cell through mitosis and cytokinesis.

引用

页码：746 / 752

页数：7

共 79 条

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