A three-dimensional electron spin resonance microscope

被引：18
作者：
Blank, A [1 ]
Dunnam, CR [1 ]
Borbat, PP [1 ]
Freed, JH [1 ]
机构：
[1] Cornell Univ, Natl Biomed Ctr Adv ESR Technol, Dept Chem & Chem Biol, Ithaca, NY 14853 USA
来源：
REVIEW OF SCIENTIFIC INSTRUMENTS | 2004年 / 75卷 / 09期
关键词：
D O I：
10.1063/1.1786353
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
An electron spin resonance (ESR) imaging system, capable of acquiring three-dimensional (3D) images with a resolution of similar to10 X 10 X 30 mum in a few minutes of acquisition, is presented. This ESR microscope employs a commercial continuous wave ESR spectrometer, working at 9.1 GHz, in conjunction with a miniature imaging probe (resonator+gradient coils), gradient current drivers, and control software. The system can acquire the image of a small (similar to1.5 X 1.5 X 0.25 mm) sample either by the modulated field gradient method, the projection reconstruction method, or by a combination of the two. A short discussion regarding the resolution of the modulated field gradient method in two-dimensional (2D) and 3D imaging is given. Detailed descriptions of the various system components are provided, along with several examples of 2D and 3D images that demonstrate the capabilities of the system. (C) 2004 American Institute of Physics.
引用
收藏
页码：3050 / 3061
页数：12
相关论文
共 38 条
  • [1] EPR and DNP properties of certain novel single electron contrast agents intended for oximetric imaging
    Ardenkjær-Larsen, JH
    Laursen, I
    Leunbach, I
    Ehnholm, G
    Wistrand, LG
    Petersson, JS
    Golman, K
    [J]. JOURNAL OF MAGNETIC RESONANCE, 1998, 133 (01) : 1 - 12
  • [2] High resolution electron spin resonance microscopy
    Blank, A
    Dunnam, CR
    Borbat, PP
    Freed, JH
    [J]. JOURNAL OF MAGNETIC RESONANCE, 2003, 165 (01) : 116 - 127
  • [3] Transparent miniature dielectric resonator for electron paramagnetic resonance experiments
    Blank, A
    Stavitski, E
    Levanon, H
    Gubaydullin, F
    [J]. REVIEW OF SCIENTIFIC INSTRUMENTS, 2003, 74 (05) : 2853 - 2859
  • [4] BLUMICH B, 2000, MONOGRAPHS PHYS CHEM
  • [5] Electron spin resonance in studies of membranes and proteins
    Borbat, PP
    Costa-Filho, AJ
    Earle, KA
    Moscicki, JK
    Freed, JH
    [J]. SCIENCE, 2001, 291 (5502) : 266 - 269
  • [6] Callaghan P.T., 1991, Principles of nuclear magnetic resonance microscopy, V1st
  • [7] 3D MR microscopy with resolution 3.7 μm by 3.3 μm by 3.3 μm
    Ciobanu, L
    Seeber, DA
    Pennington, CH
    [J]. JOURNAL OF MAGNETIC RESONANCE, 2002, 158 (1-2) : 178 - 182
  • [8] Resolution: A survey
    denDekker, AJ
    vandenBos, A
    [J]. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1997, 14 (03): : 547 - 557
  • [9] Eaton G. R, 1995, CONCEPT MAGNETIC RES, V7, P49
  • [10] Eaton GR, 1991, EPR IMAGING IN VIVO
1234