A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(i)

被引：8

作者：

Liu, Yiqing ^{[1
]}

Kang, Ting ^{[2
]}

He, Qian ^{[3
]}

Hu, Yuefu ^{[1
]}

Zuo, Zeping ^{[2
]}

Cao, Zhihua ^{[2
]}

Ke, Bowen ^{[2
]}

Zhang, Weiyi ^{[2
]}

Qi, Qingrong ^{[1
]}

机构：

[1] Sichuan Univ, West China Sch Pharm, Sichuan Engn Lab Plant Sourced Drug,Key Lab Drug, SichuanRes Ctr Drug Precis Ind Technol,Educ Minis, Chengdu 610041, Peoples R China

[2] Sichuan Univ, West China Hosp, Dept Anaesthesiol, Chengdu, Peoples R China

[3] Sichuan Univ, West China Hosp, Dept Emergency, Chengdu 610000, Sichuan, Peoples R China

来源：

RSC ADVANCES | 2021年 / 11卷 / 24期

基金：

中国国家自然科学基金;

关键词：

ATOMIC-ABSORPTION-SPECTROMETRY; COPPER; SEAWATER; CADMIUM; MERCURY; WATER; CU2+; DOTS; LEAD;

D O I：

10.1039/d1ra00725d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The disruption of copper homeostasis (Cu+/Cu2+) may cause neurodegenerative disorders. Thus, the need for understanding the role of Cu+ in physiological and pathological processes prompted the development of improved methods of Cu+ analysis. Herein, a new near-infrared (NIR) fluorescent turn-on probe (NPCu) for the detection of Cu+ was developed based on a Cu+-mediated benzylic ether bond cleavage mechanism. The probe showed high selectivity and sensitivity toward Cu+, and was successfully applied for bioimaging of Cu+ in living cells.

引用

页码：14824 / 14828

页数：5

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