Routinely used immunoassays do not detect circulating anti-GBM antibodies against native NC1 hexamer and EA epitope of the 3 chain of type IV collagen

被引：3
|
作者：
Clavarino, Giovanna [1 ,2 ]
Gauthier, Arnaud [1 ]
Hellmark, Thomas [3 ]
Carron, Pierre-Louis [4 ]
Giovannini, Diane [5 ]
Colliard, Sophie [1 ]
Dragon-Durey, Marie-Agnes [6 ]
Segelmark, Marten [7 ]
Cesbron, Jean-Yves [1 ,2 ]
Dumestre-Perard, Chantal [1 ,2 ]
机构：
[1] Ctr Hosp Univ Grenoble Alpes, Lab Immunol, Pole Biol, Grenoble 9, France
[2] Univ Grenoble Alpes, BNI Team, CNRS, TIMC,IMAG,UMR5525, Grenoble 9, France
[3] Lund Univ, Kidney Res Lab, Lund, Sweden
[4] Ctr Hosp Univ Grenoble Alpes, Serv Nephrol, Pole Digestif Dune, Grenoble 9, France
[5] Ctr Hosp Univ Grenoble Alpes, Dept Anat & Cytol Pathol, Pole Biol, Grenoble 9, France
[6] Hop Europeen Georges Pompidou, APHP, Lab Immunol, Paris, France
[7] Linkoping Univ, Dept Med & Hlth Sci, Div Drug Res, Linkoping, Sweden
来源：
EUROPEAN JOURNAL OF IMMUNOLOGY | 2018年 / 48卷 / 06期
关键词：
Anti-GBM antibodies; Glomerular basal membrane; Glomerulonephritis; Goodpasture syndrome; Indirect immunofluorescence; GOODPASTURES-SYNDROME; AUTOANTIBODIES; AUTOANTIGEN; DIAGNOSIS; ASSAYS;
D O I：
10.1002/eji.201747324
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：1082 / 1084
页数：3
相关论文
共 9 条
  • [1] Induction of anti-GBM nephritis in rats by recombinant α3(IV)NC1 and α4(IV)NC1 of type IV collagen
    Sado, Y
    Boutaud, A
    Kagawa, M
    Naito, I
    Ninomiya, Y
    Hudson, BG
    KIDNEY INTERNATIONAL, 1998, 53 (03) : 664 - 671
  • [2] High affinity of anti-GBM antibodies from Goodpasture and transplanted Alport patients to α3(IV)NC1 collagen
    Rutgers, A
    Meyers, KEC
    Canziani, G
    Kalluri, R
    Lin, J
    Madaio, MP
    KIDNEY INTERNATIONAL, 2000, 58 (01) : 115 - 122
  • [3] CHARACTERIZATION OF THE NC1 DOMAIN OF COLLAGEN TYPE-IV IN GLOMERULAR BASEMENT-MEMBRANES (GBM) AND OF ANTIBODIES TO GBM IN A PATIENT WITH ANTI-GBM NEPHRITIS
    THORNER, PS
    BAUMAL, R
    EDDY, A
    MARRANO, P
    CLINICAL NEPHROLOGY, 1989, 31 (03) : 160 - 168
  • [4] Induction of anti-GBM nephritis in rats by recombinant α3(IV)NC1 and α4(IV)NC1 of type IV collagen (vol 53, pg 664, 1998)
    Sado, Y
    Boutaud, A
    Kagawa, M
    Naito, I
    Ninomiya, Y
    Hudson, BG
    KIDNEY INTERNATIONAL, 1998, 54 (01) : 311 - 312
  • [5] Natural anti-GBM antibodies from normal human sera recognize α3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease
    Yang, Rui
    Cui, Zhao
    Hellmark, Thomas
    Segelmark, Marten
    Zhao, Ming-hui
    Wang, Hai-yan
    CLINICAL IMMUNOLOGY, 2007, 124 (02) : 207 - 212
  • [6] Anti-GBM disease in XenoMouse II is induced by human MAb versus α3(IV)NC1 collagen.
    Meyers, KEC
    Allen, J
    Gehret, J
    Gallo, M
    Hopfer, H
    Kalluri, R
    Madaio, M
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2001, 37 (04) : A24 - A24
  • [7] Nasal insufflation of a T cell epitope on human α3(IV)NC1 could prevent the development of experimental anti-GBM disease
    Jia, X. -Y
    Gu, Q. -H
    Cui, Z.
    Zhao, M. -H
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 913 - 913
  • [8] The immunoglobulin G subclass distribution of anti-GBM autoantibodies against rHα3(IV)NC1 is associated with disease severity
    Zhao, Juan
    Yan, Yu
    Cui, Zhao
    Yang, Rui
    Zhao, Ming-Hui
    HUMAN IMMUNOLOGY, 2009, 70 (06) : 425 - 429
  • [9] CONCOMITANT OCCURRENCE OF AUTOANTIBODIES AGAINST TUBULOINTTERSTITIAL NEPHRITIS ANTIGEN (TIN-AG) AND THE NONCOLLAGENOUS DOMAIN OF ALPHA-3 CHAIN OF TYPE-IV COLLAGEN [ALPHA-3-(IV)-NC1] IN A PATIENT WITH ANTI-GBM NEPHRITIS
    NELSON, T
    NEVINS, T
    FITZWATER, D
    KIM, Y
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1995, 6 (03): : 879 - 879
1