The use of statins in intensive care unit patients with sepsis

被引:3
作者
Bromilow, J. [1 ]
Bruce, M. J. L. Schuster [1 ]
机构
[1] Royal Perth Hosp, Intens Care Unit, Dept Anaesthesia, Perth, WA 6001, Australia
关键词
sepsis; intensive care unit; statin; critical illness;
D O I
10.1177/0310057X0703500215
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The incidence of sepsis is increasing and remains the leading cause of death in critically ill patients. The statin group of drugs appear to have important anti-inflammatory effects and may have a role in the treatment of sepsis. However, current prescribing guidelines recommend that statin therapy is discontinued in critically ill patients. We found no evidence to support commencing statin therapy in patients with sepsis on an intensive care unit and low levels of evidence to support continuing established therapy in this patient population.
引用
收藏
页码:256 / 258
页数:3
相关论文
共 50 条
[21]   The Incidence of Thrombocytopenia and Its Association with Mortality in Patients with Sepsis Followed in Intensive Care Unit [J].
Bayraktar, Yeim Serife ;
Acikgoz, Ashi ;
Eyiol, Hatice ;
Bayram, Hasan Huseyin ;
Kara, Iskender ;
Duman, Ates ;
Celik, Jale .
EURASIAN JOURNAL OF EMERGENCY MEDICINE, 2023, 22 (01) :24-27
[22]   Sepsis and Its Impact on Outcomes in Elderly Patients Admitted to a Malaysian Intensive Care Unit [J].
Shuker, Wan Fadzlina Wan Muhd ;
Mat Nor, Mohd Basri ;
Ralib, Azrina Md .
MALAYSIAN JOURNAL OF MEDICAL SCIENCES, 2022, 29 (03) :145-150
[23]   Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit [J].
Peterson, Laura S. ;
Suarez, Cecilia Gallego ;
Segaloff, Hannah E. ;
Griffin, Cameron ;
Martin, Emily T. ;
Odetola, Folafoluwa O. ;
Singer, Kanakadurga .
JOURNAL OF INTENSIVE CARE MEDICINE, 2020, 35 (05) :472-477
[24]   Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit [J].
Sakr, Yasser ;
Jaschinski, Ulrich ;
Wittebole, Xavier ;
Szakmany, Tamas ;
Lipman, Jeffrey ;
Namendys-Silva, Silvio A. ;
Martin-Loeches, Ignacio ;
Leone, Marc ;
Lupu, Mary-Nicoleta ;
Vincent, Jean-Louis .
OPEN FORUM INFECTIOUS DISEASES, 2018, 5 (12)
[25]   Management of Sepsis in Patients with Pulmonary Arterial Hypertension in the Intensive Care Unit [J].
Tartavoulle, Todd M. .
CRITICAL CARE NURSING CLINICS OF NORTH AMERICA, 2017, 29 (01) :15-+
[26]   Impact of secondary sepsis on mortality in adult intensive care unit patients [J].
Karvouniaris, Marios ;
Papadopoulos, Dimitrios ;
Koulenti, Despoina ;
Chatzimichail, Maria ;
Papamichalis, Panagiotis ;
Ntafoulis, Nikolaos ;
Valsamaki, Asimina ;
Katsiafylloudis, Perikles ;
Vaitsi, Eleni ;
Oikonomou, Katerina ;
Papapostolou, Evangelia ;
Xanthoudaki, Maria -Antonia ;
Papadogoulas, Antonios ;
Palli, Eleni ;
Poulakou, Garyphallia ;
Komnos, Apostolos .
INTENSIVE AND CRITICAL CARE NURSING, 2023, 75
[27]   Diagnostic and predictive performance of biomarkers in patients with sepsis in an intensive care unit [J].
Zhang, Yu ;
Khalid, Sadia ;
Jiang, Li .
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2019, 47 (01) :44-58
[28]   Transferability and interpretability of the sepsis prediction models in the intensive care unit [J].
Qiyu Chen ;
Ranran Li ;
ChihChe Lin ;
Chiming Lai ;
Dechang Chen ;
Hongping Qu ;
Yaling Huang ;
Wenlian Lu ;
Yaoqing Tang ;
Lei Li .
BMC Medical Informatics and Decision Making, 22
[29]   Transferability and interpretability of the sepsis prediction models in the intensive care unit [J].
Chen, Qiyu ;
Li, Ranran ;
Lin, ChihChe ;
Lai, Chiming ;
Chen, Dechang ;
Qu, Hongping ;
Huang, Yaling ;
Lu, Wenlian ;
Tang, Yaoqing ;
Li, Lei .
BMC MEDICAL INFORMATICS AND DECISION MAKING, 2022, 22 (01)
[30]   Treatment of Sepsis in the Surgical Intensive Care Unit [J].
Carney, Daniel E. ;
Matsushima, Kazuhide ;
Frankel, Heidi L. .
ISRAEL MEDICAL ASSOCIATION JOURNAL, 2011, 13 (11) :694-699