Cycloartane-type glycosides from the roots of Astragalus caspicus Bieb.

被引：26

作者：

Fathiazad, F. ^{[1
]}

Khosropanah, M. K. ^{[2
]}

Movafeghi, A. ^{[2
]}

机构：

[1] Tabriz Univ Med Sci, Dept Pharmacognosy, Fac Pharm, Tabriz, Iran

[2] Univ Tabriz, Dept Plant Biol, Fac Nat Sci, Tabriz, Iran

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 11期

关键词：

Astragalus caspicus; Fabaceae; cycloartane-type glycoside; saponin; TRITERPENE GLYCOSIDES; AERIAL PARTS; IV; DIVERSIFICATION; RATES;

D O I：

10.1080/14786410902975582

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3,6,16,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while caspicuside II owns (20R, 24S)-epoxy-3, 6,16, 25-tetrahydroxycycloartane (cycloastragenol). The chemical structures of these new cycloartane-type glycosides were established as 3-O--L-rhamnopyranosyl-16-O--D-xylopyranosyl-cyclocanthogenol and 3-O-[-D-xylopyranosyl(1 3)--D-glucopyranosyl]-6-O--xylopyranosyl-cycloastragenol, respectively. These findings add to a growing body of literature demonstrating the high variation of cycloartane-type triterpene glycosides in different species of Astragalus.

引用

页码：1069 / 1078

页数：10

共 23 条

[11] Two new cycloartane Saponins from the roots of Astragalus membranaceus [J].

Kim, Ju Sun ;

Yean, Min-Hye ;

Lee, Eun-Ju ;

Jung, Hye Sil ;

Lee, Joo Young ;

Kim, Yoon Jung ;

Kang, Sam Sik .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, 56 (01) :105-108

[12]

LIXIAN G, 1986, PHYTOCHEMISTRY, V0025

[13]

Mabberley D.J., 1997, The plant-book: A portable dictionary of the vascular plants, V2nd, P858

[14] Triterpenoids from Astragalus plants [J].

Mamedova, RP ;

Isaev, MI .

CHEMISTRY OF NATURAL COMPOUNDS, 2004, 40 (04) :303-357

[15]

MOVAFEGHI A, 2009, NATURAL PRODUCT RES, V24, P703

[16] Leishmanicidal cycloartane-type triterpene glycosides from Astragalus oleifolius [J].

Özipek, M ;

Dönmez, AA ;

Çalis, I ;

Brun, R ;

Rüedi, P ;

Tasdemir, D .

PHYTOCHEMISTRY, 2005, 66 (10) :1168-1173

[17]

Podlech D, 1998, FLORISTIC CHARACTERI, P405

[18] Diversification rates in a temperate legume clade: Are there ''so many species'' of Astragalus (Fabaceae)? [J].

Sanderson, MJ ;

Wojciechowski, MF .

AMERICAN JOURNAL OF BOTANY, 1996, 83 (11) :1488-1502

[19] Phylogeny, biogeography, and rates of diversification of New World Astragalus (Leguminosae) with an emphasis on South American radiations [J].

Scherson, Rosa A. ;

Vidal, Rodrigo ;

Sanderson, Michael J. .

AMERICAN JOURNAL OF BOTANY, 2008, 95 (08) :1030-1039

[20] Cycloartane triterpene glycosides from the roots of Astragalus gilvus Boiss [J].

Tabanca, N ;

Bedir, E ;

Alankus-Caliskan, O ;

Khan, KA .

BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2005, 33 (10) :1067-1070

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