Cycloartane-type glycosides from the roots of Astragalus caspicus Bieb.

被引：26

作者：

Fathiazad, F. ^{[1
]}

Khosropanah, M. K. ^{[2
]}

Movafeghi, A. ^{[2
]}

机构：

[1] Tabriz Univ Med Sci, Dept Pharmacognosy, Fac Pharm, Tabriz, Iran

[2] Univ Tabriz, Dept Plant Biol, Fac Nat Sci, Tabriz, Iran

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 11期

关键词：

Astragalus caspicus; Fabaceae; cycloartane-type glycoside; saponin; TRITERPENE GLYCOSIDES; AERIAL PARTS; IV; DIVERSIFICATION; RATES;

D O I：

10.1080/14786410902975582

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3,6,16,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while caspicuside II owns (20R, 24S)-epoxy-3, 6,16, 25-tetrahydroxycycloartane (cycloastragenol). The chemical structures of these new cycloartane-type glycosides were established as 3-O--L-rhamnopyranosyl-16-O--D-xylopyranosyl-cyclocanthogenol and 3-O-[-D-xylopyranosyl(1 3)--D-glucopyranosyl]-6-O--xylopyranosyl-cycloastragenol, respectively. These findings add to a growing body of literature demonstrating the high variation of cycloartane-type triterpene glycosides in different species of Astragalus.

引用

页码：1069 / 1078

页数：10

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