A new polyketide, penicillolide from the marine-derived fungus Penicillium sacculum

被引：3

作者：

Liu, Tao ^{[1
]}

Zhang, Songya ^{[2
]}

Li, Zhanlin ^{[2
]}

Wang, Yu ^{[1
]}

Chen, Zaixing ^{[3
]}

Bai, Jiao ^{[2
]}

Tian, Li ^{[4
,5
]}

Pei, Yuehu ^{[2
]}

Hua, Huiming ^{[2
]}

机构：

[1] China Med Univ, Sch Pharm, Dept Nat Prod Chem, Shenyang 110001, Peoples R China

[2] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Key Lab Struct Based Drug Design Discovery, Minist Educ, Shenyang, Peoples R China

[3] China Med Univ, Dept Cent Lab, Sch Pharm, Shenyang 110001, Peoples R China

[4] First Inst Oceanog SOA, Qingdao Key Lab Analyt Technol Dev & Standardizat, Qingdao, Peoples R China

[5] Qingdao Univ Sci & Technol, Dept Biol, Qingdao, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 09期

基金：

中国国家自然科学基金;

关键词：

Marine-derived fungus; Penicillium sacculum; polyketide; penicillolide; BIOACTIVE COMPOUNDS; NATURAL-PRODUCTS; DERIVATIVES;

D O I：

10.1080/14786419.2015.1101693

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new polyketide, penicillolide (1) was isolated from the fermentation broth of the marine-derived fungus Penicillium sacculum GT-308. Compound 1 is a polyketide with a unique carbon skeleton. The structure of this compound was established via extensive spectroscopic analyses including 1D-, 2D-NMR, and HRESI-MS.

引用

页码：1025 / 1029

页数：5

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