Occupational COPD-The most under-recognized occupational lung disease?

被引:72
作者
Murgia, Nicola [1 ]
Gambelunghe, Angela [1 ]
机构
[1] Univ Perugia, Sect Occupat Med Resp Dis & Toxicol, Perugia, Italy
关键词
airways; bronchitis; COPD; emphysema; occupational; VGDF; workers; OBSTRUCTIVE PULMONARY-DISEASE; AMERICAN-THORACIC-SOCIETY; AIR-FLOW LIMITATION; 2-YEAR FOLLOW-UP; COAL-MINE DUST; RESPIRATORY SYMPTOMS; CHRONIC-BRONCHITIS; SHIPYARD WELDERS; FUNCTION DEFECTS; SILICA EXPOSURE;
D O I
10.1111/resp.14272
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Chronic obstructive pulmonary disease (COPD) is caused by exposure to noxious particles and gases. Smoking is the main risk factor, but other factors are also associated with COPD. Occupational exposure to vapours, gases, dusts and fumes contributes to the development and progression of COPD, accounting for a population attributable fraction of 14%. Workplace pollutants, in particular inorganic dust, can initiate airway damage and inflammation, which are the hallmarks of COPD pathogenesis. Occupational COPD is still underdiagnosed, mainly due to the challenges of assessing the occupational component of the disease in clinical settings, especially if other risk factors are present. There is a need for specific education and training for clinicians, and research with a focus on evaluating the role of occupational exposure in causing COPD. Early diagnosis and identification of occupational causes is very important to prevent further decline in lung function and to reduce the health and socio-economic burden of COPD. Establishing details of the occupational history by general practitioners or respiratory physicians could help to define the occupational burden of COPD for individual patients, providing the first useful interventions (smoking cessation, best therapeutic management, etc.). Once patients are diagnosed with occupational COPD, there is a wide international variation in access to specialist occupational medicine and public health services, along with limitations in workplace and income support. Therefore, a strong collaboration between primary care physicians, respiratory physicians and occupational medicine specialists is desirable to help manage COPD patients' health and social issues.
引用
收藏
页码:399 / 410
页数:12
相关论文
共 141 条
[1]  
AHMAN M, 1991, INT ARCH OCC ENV HEA, V63, P175
[2]   Denim production and silicosis [J].
Akgun, Metin .
CURRENT OPINION IN PULMONARY MEDICINE, 2016, 22 (02) :165-169
[3]   Lung function and paper dust exposure among workers in a soft tissue paper mill [J].
Andersson, Eva ;
Sallsten, Gerd ;
Lohman, Susanna ;
Neitzel, Richard ;
Toren, Kjell .
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2020, 93 (01) :105-110
[4]   PULMONARY-FUNCTION OF UNITED-STATES COAL-MINERS RELATED TO DUST EXPOSURE ESTIMATES [J].
ATTFIELD, MD ;
HODOUS, TK .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1992, 145 (03) :605-609
[5]   American Thoracic Society Statement: Occupational contribution to the burden of airway disease [J].
Balmes, J ;
Becklake, M ;
Blanc, P ;
Henneberger, P ;
Kreiss, K ;
Mapp, C ;
Milton, D ;
Schwartz, D ;
Toren, K ;
Viegi, G .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2003, 167 (05) :787-797
[6]   Knowledge and utilisation of occupational asthma guidelines in primary care [J].
Barber, Chris M. ;
Frank, Tim ;
Walsh, Kieran ;
Burton, Clare ;
Bradshaw, Lisa ;
Fishwick, David .
PRIMARY CARE RESPIRATORY JOURNAL, 2010, 19 (03) :274-280
[7]   Cellular and molecular mechanisms of asthma and COPD [J].
Barnes, Peter J. .
CLINICAL SCIENCE, 2017, 131 (13) :1541-1558
[8]  
BECKLAKE MR, 1957, AM REV TUBERC PULM, V76, P398
[9]   OCCUPATIONAL EXPOSURES - EVIDENCE FOR A CAUSAL ASSOCIATION WITH CHRONIC OBSTRUCTIVE PULMONARY-DISEASE [J].
BECKLAKE, MR .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1989, 140 (03) :S85-S91
[10]   CHRONIC AIR-FLOW LIMITATION - ITS RELATIONSHIP TO WORK IN DUSTY OCCUPATIONS [J].
BECKLAKE, MR .
CHEST, 1985, 88 (04) :608-617