Analysis of Clinically Effective of Autologous Serum Eye Drops for Dry Eye at Different Concentrations

Reduced tear production or suboptimal interaction between surface structures and their normal functions lead to dry eye. Primary objective for this study to find out the least concentrated but clinically effective preparation for autologous serum eye drops (ASED) for dry eye and compare low concentration with best therapeutic effect and to optimize the preparation procedure of serum based eye drops. This was a prospective, randomized, single mass clinical investigation conducted in hospital based settings at Ophthalmology Department, Sheikh Zayed Hospital, Rahim Yar Khan, in collaboration with ophthalmologists and optometrists. The duration of study was 8 months and 200 subjects with dry eye were selected for investigation. Results of the study concluded that out of total subjects 19% subjects of dry eye were improved with 10% ASED, 36% subjects were improved with 20% ASED and 45% subjects improved with 50% ASED. It showed that 50% ASED was the most effective treatment option for dry eye, however, 20% ASED and least concentration i.e 10% ASED is also clinically effective.