The stepping motor protein as a feedback control ratchet

被引：29

作者：

Bier, Martin ^{[1
]}

机构：

[1] E Carolina Univ, Dept Phys, Greenville, NC 27858 USA

来源：

BIOSYSTEMS | 2007年 / 88卷 / 03期

关键词：

processive motor protein; feedback control Brownian ratchet; polypeptide internal friction;

D O I：

10.1016/j.biosystems.2006.07.013

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

It is explained how going from a one headed motor protein to a stepping two headed motor protein is equivalent to going from a stochastically flashing ratchet to a feedback control ratchet. Both these ratchets have been well studied in the literature and their speeds and efficiencies are briefly reviewed. Next it is shown how a feedback control ratchet mechanism model can account for very accurate recent data obtained on kinesin. Finally, the role of internal friction in the operation of stepping motor proteins is discussed. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：301 / 307

页数：7

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[4]

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