Treatment and prevention of invasive pneumococcal disease

被引：7

作者：

Dominguez-Alegria, A. R. ^{[1
]}

Pintado, V. ^{[2
]}

Barbolla, I. ^{[1
]}

机构：

[1] Hosp Ramon & Cajal, Serv Med Interna, Madrid, Spain

[2] Hosp Ramon & Cajal, IRYCIS, Serv Enfermedades Infecciosas, Madrid, Spain

来源：

REVISTA CLINICA ESPANOLA | 2018年 / 218卷 / 05期

关键词：

Streptococcus pneumoniae; Invasive pneumococcal disease; Resistance; Combined therapy; Vaccine; COMMUNITY-ACQUIRED PNEUMONIA; COMBINATION ANTIBIOTIC-THERAPY; RESISTANT STREPTOCOCCUS-PNEUMONIAE; VACCINE-NAIVE ADULTS; POLYSACCHARIDE VACCINE; ANTIMICROBIAL RESISTANCE; CONJUGATE VACCINE; CEFTOBIPROLE MEDOCARIL; BACTEREMIC PNEUMONIA; CEFTAROLINE FOSAMIL;

D O I：

10.1016/j.rce.2018.01.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Invasive pneumococcal disease is a severe infection that mainly affects patients with associated comorbidity. The paediatric conjugate vaccination has resulted in a change in the adult vaccination strategy. The antibiotic resistance of pneumococcus is not currently a severe problem. Nevertheless, the World Health Organisation has included pneumococcus among the bacteria whose treatment requires the introduction of new drugs, such as ceftaroline and ceftobiprole. Although the scientific evidence is still limited, the combination of beta-lactams and macrolides is recommended as empiric therapy for bacteraemic pneumococcal pneumonia. (C) 2018 Elsevier Espana, S.L.U. and Sociedad Espanola de Medicina Interna (SEMI). All rights reserved.

引用

页码：244 / 252

页数：9

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