Methicillin-resistant Staphylococcus aureus in Nepal

被引:11
作者
Shrestha, Lok Bahadur [1 ,2 ]
Syangtan, Gopiram [3 ]
Basnet, Ajaya [3 ]
Acharya, Krishna Prasad [4 ]
Chand, Arun Bahadur [5 ]
Pokhrel, Khilasa [6 ]
机构
[1] Univ New South Wales, Sch Med Sci, Sydney, NSW, Australia
[2] Univ New South Wales, Kirby Inst, Sydney, NSW, Australia
[3] Tribhuvan Univ, Shi Gan Int Coll Sci & Technol, Kathmandu, Nepal
[4] Anim Quarantine Off, Kathmandu, Nepal
[5] Kist Med Coll & Teaching Hosp, Dept Clin Lab, Kathmandu, Nepal
[6] Kathmandu Med Coll, Dept Microbiol, Kathmandu, Nepal
关键词
clindamycin; methicillin-resistant Staphylococcus aureus; multi-drug resistance; HEALTH-CARE WORKERS; COAGULASE-NEGATIVE STAPHYLOCOCCI; URINARY-TRACT-INFECTIONS; BIOFILM FORMATION; NASAL COLONIZATION; PREVALENCE; CARRIAGE; ASSOCIATION; THREAT;
D O I
10.31729/jnma.6251
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Staphylococcus aureus is both a frequent commensal and a leading cause of endocarditis, bacteremia, osteomyelitis and skin and soft tissue infections and device-related infections. We performed this minireview to summarize the prevalence of Staphylococcus aureus among clinical samples and estimate the proportion of methicillin-resistant Staphylococcus aureus. The prevalence of Staphylococcus aureus among clinical isolates in Nepal is 34.5%. On average, the proportion of multi-drug resistance in Staphylococcus aureus is 57.1%. Methicillin-resistant Staphylococcus aureus accounts for a total of 41.7%. Inducible clindamycin resistance was detected in about 35% of the isolates. A regular antimicrobial resistance surveillance mechanism is necessary to mitigate the development of resistance among organisms and further spread of superbugs like methicillinresistance Staphylococcus aureus.
引用
收藏
页码:518 / 522
页数:5
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