Guangsangons F-J, anti-oxidant and anti-inflammatory Diels-Alder type adducts, from Morus macroura Miq.

被引：55

作者：

Dai, SJ

Ma, ZB

Wu, Y

Chen, RY

Yu, DQ ^{[1
]}

机构：

[1] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[2] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

PHYTOCHEMISTRY | 2004年 / 65卷 / 23期

关键词：

Maras macroura Miq; Moraceae; Diels-Alder adduct; guangsangon F-J;

D O I：

10.1016/j.phytochem.2004.07.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Five Diels-Alder type adducts, named guangsangons F, G, H, 1, and J, along with two known compounds, mulberrofuran J and kuwanon J, were isolated from Morus macroura Miq. Their structures were determined by means of spectroscopic analyses and chemical methods. These compounds were regarded biogenetically as Diels-Alder type adducts of dehydroprenylphenols and chalcone derivatives, and H-1 NMR variable temperature experiments suggested that they all existed as an equilibrium mixture of conformational isomers in solution. Among the isolated new compounds, guangsangons H, 1, and J displayed potent antioxidant activities and moderate anti-inflammatory activities. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：3135 / 3141

页数：7

共 15 条

[1] CIRCULAR DICHROISM, OPTICAL ROTATORY DISPERSION AND ABSOLUTE CONFIGURATION OF FLAVANONES, 3-HYDROXYFLAVANONES AND THEIR GLYCOSIDES - DETERMINATION OF AGLYCONE CHIRALITY IN FLAVANONE GLYCOSIDES [J].