Basic Science of Pulmonary Arterial Hypertension for Clinicians New Concepts and Experimental Therapies

被引：406
作者：
Archer, Stephen L. [1 ]
Weir, E. Kenneth [2 ,3 ]
Wilkins, Martin R. [4 ]
机构：
[1] Univ Chicago, Cardiol Sect, Chicago, IL 60637 USA
[2] VA Med Ctr, Minneapolis, MN USA
[3] Univ Minnesota, Minneapolis, MN USA
[4] Univ London Imperial Coll Sci Technol & Med, Dept Expt Med & Toxicol, London, England
来源：
CIRCULATION | 2010年 / 121卷 / 18期
基金：
英国医学研究理事会; 美国国家卫生研究院;
关键词：
BONE MORPHOGENETIC PROTEIN; SOLUBLE GUANYLATE-CYCLASE; NITRIC-OXIDE SYNTHASE; SMOOTH-MUSCLE-CELLS; ENDOTHELIAL PROGENITOR CELLS; PYRUVATE-DEHYDROGENASE KINASE; VASOACTIVE-INTESTINAL-PEPTIDE; CALCIUM-CHANNEL BLOCKERS; CAPACITATIVE CA2+ ENTRY; SEROTONIN TRANSPORTER;
D O I：
10.1161/CIRCULATIONAHA.108.847707
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：2045 / U175
页数：27
相关论文
共 206 条
[1]   Appetite-suppressant drugs and the risk of primary pulmonary hypertension [J].
Abenhaim, L ;
Moride, Y ;
Brenot, F ;
Rich, S ;
Benichou, J ;
Kurz, X ;
Higenbottam, T ;
Oakley, C ;
Wouters, E ;
Aubier, M ;
Simonneau, G ;
Begaud, B .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (09) :609-616
[2]   Low-molecular-weight heparin inhibits hypoxic pulmonary hypertension and vascular remodeling in guinea pigs [J].
Al-Ansari, Essam ;
Du, Hong-Kai ;
Yu, Lunyin ;
Ochoa, Cristhiaan D. ;
Garg, Hari G. ;
Quinn, Deborah A. ;
Hales, Charles A. .
CHEST, 2007, 132 (06) :1898-1905
[3]   AMPK and metabolic adaptation by the heart to pressure overload [J].
Allard, Michael F. ;
Parsons, Hannah L. ;
Saeedi, Ramesh ;
Wambolt, Richard B. ;
Brownsey, Roger .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2007, 292 (01) :H140-H148
[4]   Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease [J].
Alp, NJ ;
Channon, KM .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (03) :413-420
[5]   Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension [J].
Archer, SL ;
Djaballah, K ;
Humbert, M ;
Weir, EK ;
Fartoukh, M ;
DalL'Ava-Santucci, J ;
Mercier, JC ;
Simonneau, G ;
Dinh-Xuan, AT .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (04) :1061-1067
[6]   Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction -: Ionic diversity in smooth muscle cells [J].
Archer, SL ;
Wu, XC ;
Thébaud, B ;
Nsair, A ;
Bonnet, S ;
Tyrrell, B ;
McMurtry, MS ;
Hashimoto, K ;
Harry, G ;
Michelakis, ED .
CIRCULATION RESEARCH, 2004, 95 (03) :308-318
[7]  
ARCHER SL, 2001, AM J PHYSIOL-HEART C, V294, pH570
[8]   Phosphodiesterase Type 5 Inhibitors for Pulmonary Arterial Hypertension. [J].
Archer, Stephen L. ;
Michelakis, Evangelos D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (19) :1864-1871
[9]   Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension [J].
Asosingh, Kewal ;
Aldred, Micheala A. ;
Vasanji, Arnit ;
Drazba, Judith ;
Sharp, Jacqueline ;
Farver, Carol ;
Comhair, Suzy A. A. ;
Xu, Weiling ;
Licina, Lauren ;
Huang, Lan ;
Anand-Apte, Bela ;
Yoder, Mervin C. ;
Tuder, Rubin M. ;
Erzurum, Serpil C. .
AMERICAN JOURNAL OF PATHOLOGY, 2008, 172 (03) :615-627
[10]   Signal transduction by the TGF-β superfamily [J].
Attisano, L ;
Wrana, JL .
SCIENCE, 2002, 296 (5573) :1646-1647
12345678910