A very simple and highly efficient procedure for N-formylation of primary and secondary amines at room temperature under solvent-free conditions

被引：127

作者：

Brahmachari, Goutam ^{[1
]}

Laskar, Sujay ^{[1
]}

机构：

[1] Visva Bharati Univ, Dept Chem, Santini Ketan 731235, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 17期

关键词：

N-Formylation; Amines; Sodium formate; Formic acid; Room temperature; Solvent-free; STEREOSELECTIVE SYNTHESIS; DERIVATIVES; ESTERS; ACID; DIMETHYLFORMAMIDE; ISOCYANIDES; REAGENTS; FORMATE; FACILE; AGENT;

D O I：

10.1016/j.tetlet.2010.02.119

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Formylation of primary and secondary amines has efficiently been carried out at room temperature in excellent yields by using catalytic amount of sodium formate in formic acid under solvent-free conditions. The process is remarkably simple and environmentally benign. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：2319 / 2322

页数：4

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