The interaction of HSV-1 tegument proteins pUL36 and pUL37: a novel target for antivirals that inhibit viral assembly

被引:2
作者
Diefenbach, Russell J. [1 ,2 ]
Fraefel, Cornel [3 ]
Cunningham, Anthony L. [1 ,2 ]
机构
[1] Univ Sydney, Ctr Virus Res, Westmead Millennium Inst, Westmead, NSW 2145, Australia
[2] Westmead Hosp, Westmead, NSW 2145, Australia
[3] Univ Zurich, Inst Virol, CH-8057 Zurich, Switzerland
关键词
antiviral; herpes simplex virus; pUL36; pUL37; tegument; virus assembly; HERPES-SIMPLEX-VIRUS; SECONDARY ENVELOPMENT; NULL MUTATION; UL37; PROTEIN; GENE-PRODUCT; TYPE-1; CAPSIDS; IDENTIFICATION; BINDING; AGENTS;
D O I
10.2217/fvl.14.56
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
引用
收藏
页码:787 / 789
页数:3
相关论文
共 25 条
  • [1] Identification of interaction domains within the UL37 tegument protein of herpes simplex virus type 1
    Bucks, Michelle A.
    Murphy, Michael A.
    O'Regan, Kevin J.
    Courtney, Richard J.
    [J]. VIROLOGY, 2011, 416 (1-2) : 42 - 53
  • [2] Acyclovir and Transmission of HIV-1 from Persons Infected with HIV-1 and HSV-2
    Celum, C.
    Wald, A.
    Lingappa, J. R.
    Magaret, A. S.
    Wang, R. S.
    Mugo, N.
    Mujugira, A.
    Baeten, J. M.
    Mullins, J. I.
    Hughes, J. P.
    Bukusi, E. A.
    Cohen, C. R.
    Katabira, E.
    Ronald, A.
    Kiarie, J.
    Farquhar, C.
    Stewart, G. J.
    Makhema, J.
    Essex, M.
    Were, E.
    Fife, K. H.
    de Bruyn, G.
    Gray, G. E.
    McIntyre, J. A.
    Manongi, R.
    Kapiga, S.
    Coetzee, D.
    Allen, S.
    Inambao, M.
    Kayitenkore, K.
    Karita, E.
    Kanweka, W.
    Delany, S.
    Rees, H.
    Vwalika, B.
    Stevens, W.
    Campbell, M. S.
    Thomas, K. K.
    Coombs, R. W.
    Morrow, R.
    Whittington, W. L. H.
    McElrath, M. J.
    Barnes, L.
    Ridzon, R.
    Corey, L.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (05) : 427 - 439
  • [3] A null mutation in the gene encoding the herpes simplex virus type 1 UL37 polypeptide abrogates virus maturation
    Desai, P
    Sexton, GL
    McCaffery, JM
    Person, S
    [J]. JOURNAL OF VIROLOGY, 2001, 75 (21) : 10259 - 10271
  • [4] A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells
    Desai, PJ
    [J]. JOURNAL OF VIROLOGY, 2000, 74 (24) : 11608 - 11618
  • [5] Essential function of the pseudorabies virus UL36 gene product is independent of its interaction with the UL37 protein
    Fuchs, W
    Klupp, BG
    Granzow, H
    Mettenleiter, TC
    [J]. JOURNAL OF VIROLOGY, 2004, 78 (21) : 11879 - 11889
  • [6] Exploiting Herpes Simplex Virus Entry for Novel Therapeutics
    Hadigal, Satvik
    Shukla, Deepak
    [J]. VIRUSES-BASEL, 2013, 5 (06): : 1447 - 1465
  • [7] Hodge RAV, 2013, ADV PHARMACOL, V67, P1, DOI 10.1016/B978-0-12-405880-4.00001-9
  • [8] Herpes Simplex Virus 1 Protein UL37 Interacts with Viral Glycoprotein gK and Membrane Protein UL20 and Functions in Cytoplasmic Virion Envelopment
    Jambunathan, Nithya
    Chouljenko, Dmitry
    Desai, Prashant
    Charles, Anu-Susan
    Subramanian, Ramesh
    Chouljenko, Vladimir N.
    Kousoulas, Konstantin G.
    [J]. JOURNAL OF VIROLOGY, 2014, 88 (11) : 5927 - 5935
  • [9] The interaction of the HSV-1 tegument proteins pUL36 and pUL37 is essential for secondary envelopment during viral egress
    Kelly, Barbara J.
    Bauerfeind, Rudolf
    Binz, Anne
    Sodeik, Beate
    Laimbacher, Andrea S.
    Fraefel, Cornel
    Diefenbach, Russell J.
    [J]. VIROLOGY, 2014, 454 : 67 - 77
  • [10] Identification of a single amino acid residue which is critical for the interaction between HSV-1 inner tegument proteins pUL36 and pUL37
    Kelly, Barbara J.
    Mijatov, Branka
    Fraefel, Cornel
    Cunningham, Anthony L.
    Diefenbach, Russell J.
    [J]. VIROLOGY, 2012, 422 (02) : 308 - 316