Role of Medium-Chain Fatty Acids in Healthy Metabolism: A Clinical Perspective

被引：74
作者：
Huang, Lili [1 ,2 ]
Gao, Lin [1 ,2 ]
Chen, Chen [1 ,2 ]
机构：
[1] Univ Queensland, Sch Biomed Sci, Brisbane, Qld, Australia
[2] Univ Queensland, Inst Mol Biosci, Brisbane, Qld, Australia
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2021年 / 32卷 / 06期
基金：
英国医学研究理事会;
关键词：
LONG-CHAIN; OXIDATION DISORDERS; ENERGY-EXPENDITURE; GROWTH-HORMONE; ADIPOSE-TISSUE; TRIGLYCERIDE SUPPLEMENTATION; CHOLECYSTOKININ SECRETION; DIETARY SUBSTITUTION; INSULIN-SECRETION; ANOREXIA-NERVOSA;
D O I：
10.1016/j.tem.2021.03.002
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Medium-chain fatty acids (MCFAs) serve not only as an energy source but also regulate glucose and lipid metabolism. The unique transport and rapid metabolism of MCFAs provide additional clinical benefits over other substrates such as long-chain fatty acids (LCFAs) and have prompted interest in the use of MCFAs for treating metabolic and neurological disorders. This review focuses on the metabolic role of MCFAs in modulating cellular signaling and regulating key circulating metabolites and hormones. The potential of MCFAs in treating various metabolic diseases in a clinical setting has also been analyzed.
引用
收藏
页码：351 / 366
页数：16
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