Prognostic factors for adults with cardiac arrest in the emergency department: a retrospective cohort study

Cardiac arrest in the emergency department is associated with the following three scenarios: out-of-hospital cardiac arrest, primary emergency department cardiac arrest (EDCA), and patients transferred from other hospitals after the return of spontaneous circulation from cardiac arrest. Among them, the primary cardiac arrest episode in the emergency department has been less studied. This aim of this study was to explore patient characteristics and the relationship between causes of EDCA and survival outcomes according to different patient management strategies. The main finding of this study was that EDCA with Cardiogenic etiology was associated with higher survival to discharge (OR: 2.31; 95% CI: 1.59???3.91) and discharged neurological outcome (OR: 2.84; 95% CI: 1.57???5.97). More favorable discharged neurological outcome were also found in EDCA patients with initial shockable rhythm (OR: 4.83; 95% CI: 2.33???10.01) and shorter resuscitation time (???11.5 min, OR: 3.62; 95% CI: 1.57???8.32). EDCA patients under sedative medication (OR: 0.24; 95% CI: 0.10???0.59) and ventilator support by intubation before EDCA episode (OR: 0.26; 95% CI: 0.09???0.75) had poor neurological outcome. We conclude that EDCA patients with cardiogenic etiology have more favorable survival to discharge and discharged neurological outcomes. Prolonged CPR time during EDCA, post-intubation status and sedative medication use were prognostic factors of negative survival and neurological outcomes.