Biomarkers of stroke -: clinical relevance in diagnosis and prognosis

被引:0
作者
Sitzer, M. [1 ]
Dvorak, F. [1 ]
Foerch, C. [1 ]
机构
[1] Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany
关键词
ischemic stroke; hemorrhagic stroke; blood serum marker; biomarker; diagnosis; prognosis;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In the past, a numerous amount of blood serum biomarkers were analysed concerning their significance of relation with cerebrovascular diseases. Alongside the diagnosis and differentiation of an acute stroke-syndrome, the individual future prospects in various clinical situations are in the foreground. The application of S100B and cellular fibronectin seems to be the most reliable and precise application of blood serum biomarker to predict a malignant course of acute middle cerebral artery infarction at the moment. Despite the various amount of clinical trials, there is no concrete prospect of clinical application at this point. Surely the conduction of dimensioned clinical trials concerning these pilot studies will be necessary in order to evaluate the specified meaning of blood serum biomarkers and their combination with clinically relevant questionings. The state of affairs can be gathered from the present article.
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页码:352 / +
页数:4
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