共 17 条
Biomarkers of stroke -: clinical relevance in diagnosis and prognosis
被引:0
作者:

Sitzer, M.
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机构:
Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany

Dvorak, F.
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机构:
Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany

Foerch, C.
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机构:
Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany
机构:
[1] Univ Frankfurt Main Klinikum, Zentrum Neurol & Neurochirurg, Klin Neurol, D-60529 Frankfurt, Germany
关键词:
ischemic stroke;
hemorrhagic stroke;
blood serum marker;
biomarker;
diagnosis;
prognosis;
D O I:
暂无
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
In the past, a numerous amount of blood serum biomarkers were analysed concerning their significance of relation with cerebrovascular diseases. Alongside the diagnosis and differentiation of an acute stroke-syndrome, the individual future prospects in various clinical situations are in the foreground. The application of S100B and cellular fibronectin seems to be the most reliable and precise application of blood serum biomarker to predict a malignant course of acute middle cerebral artery infarction at the moment. Despite the various amount of clinical trials, there is no concrete prospect of clinical application at this point. Surely the conduction of dimensioned clinical trials concerning these pilot studies will be necessary in order to evaluate the specified meaning of blood serum biomarkers and their combination with clinically relevant questionings. The state of affairs can be gathered from the present article.
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页码:352 / +
页数:4
相关论文
共 17 条
[1]
PARK7 and nucleoside diphosphate kinase A as plasma markers for the early diagnosis of stroke
[J].
Allard, L
;
Burkhard, PR
;
Lescuyer, P
;
Burgess, JA
;
Walter, N
;
Hochstrasser, DF
;
Sanchez, JC
.
CLINICAL CHEMISTRY,
2005, 51 (11)
:2043-2051

Allard, L
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland

Burkhard, PR
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland

Lescuyer, P
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland

Burgess, JA
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland

Walter, N
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland

Hochstrasser, DF
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland

Sanchez, JC
论文数: 0 引用数: 0
h-index: 0
机构: DBSB CMU, Biomed Protem Res Grp, CH-1211 Geneva, Switzerland
[2]
ApoC-I and ApoC-III as potential plasmatic markers to distinguish between ischemic and hemorrhagic stroke
[J].
Allard, L
;
Lescuyer, P
;
Burgess, J
;
Leung, KY
;
Ward, M
;
Walter, N
;
Burkhard, PR
;
Corthals, G
;
Hochstrasser, DF
;
Sanchez, JC
.
PROTEOMICS,
2004, 4 (08)
:2242-2251

Allard, L
论文数: 0 引用数: 0
h-index: 0
机构:
Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Lescuyer, P
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Burgess, J
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Leung, KY
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Ward, M
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Walter, N
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Burkhard, PR
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Corthals, G
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Hochstrasser, DF
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland

Sanchez, JC
论文数: 0 引用数: 0
h-index: 0
机构: Geneva Univ Hosp, Biomed Proteom Res Grp, Cent Clin Chem Lab, CH-1211 Geneva 14, Switzerland
[3]
Plasma cellular-fibronectin concentration predicts hemorrhagic transformation after thrombolytic therapy in acute ischemic stroke
[J].
Castellanos, M
;
Leira, R
;
Serena, J
;
Blanco, M
;
Pedraza, S
;
Castillo, J
;
Dávalos, A
.
STROKE,
2004, 35 (07)
:1671-1676

Castellanos, M
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain

Leira, R
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain

Serena, J
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain

Blanco, M
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain

Pedraza, S
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain

Castillo, J
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain

Dávalos, A
论文数: 0 引用数: 0
h-index: 0
机构: UAB, Hosp Univ Doctor Josep Trueta, Dept Neurol, Girona 17007, Spain
[4]
Blood test detecting autoantibodies to N-methyl-D-aspartate neuroreceptors for evaluation of patients with transient ischemic attack and stroke
[J].
Dambinova, SA
;
Khounteev, GA
;
Izykenova, GA
;
Zavolokov, IG
;
Ilyukhina, AY
;
Skoromets, AA
.
CLINICAL CHEMISTRY,
2003, 49 (10)
:1752-1762

Dambinova, SA
论文数: 0 引用数: 0
h-index: 0
机构: IP Pavlovs State Med Univ, Dept Neurol & Neurosurg, St Petersburg 197102, Russia

Khounteev, GA
论文数: 0 引用数: 0
h-index: 0
机构: IP Pavlovs State Med Univ, Dept Neurol & Neurosurg, St Petersburg 197102, Russia

Izykenova, GA
论文数: 0 引用数: 0
h-index: 0
机构: IP Pavlovs State Med Univ, Dept Neurol & Neurosurg, St Petersburg 197102, Russia

Zavolokov, IG
论文数: 0 引用数: 0
h-index: 0
机构: IP Pavlovs State Med Univ, Dept Neurol & Neurosurg, St Petersburg 197102, Russia

Ilyukhina, AY
论文数: 0 引用数: 0
h-index: 0
机构: IP Pavlovs State Med Univ, Dept Neurol & Neurosurg, St Petersburg 197102, Russia

Skoromets, AA
论文数: 0 引用数: 0
h-index: 0
机构: IP Pavlovs State Med Univ, Dept Neurol & Neurosurg, St Petersburg 197102, Russia
[5]
Erythropoietin therapy for acute stroke is both safe and beneficial
[J].
Ehrenreich, H
;
Hasselblatt, M
;
Dembowski, C
;
Cepek, L
;
Lewczuk, P
;
Stiefel, M
;
Rustenbeck, HH
;
Breiter, N
;
Jacob, S
;
Knerlich, F
;
Bohn, M
;
Poser, W
;
Rüther, E
;
Kochen, M
;
Gefeller, O
;
Gleiter, C
;
Wessel, TC
;
De Ryck, M
;
Itri, L
;
Prange, H
;
Cerami, A
;
Brines, M
;
Sirén, AL
.
MOLECULAR MEDICINE,
2002, 8 (08)
:495-505

Ehrenreich, H
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Hasselblatt, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Dembowski, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Cepek, L
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Lewczuk, P
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Stiefel, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Rustenbeck, HH
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Breiter, N
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Jacob, S
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Knerlich, F
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Bohn, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Poser, W
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Rüther, E
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Kochen, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Gefeller, O
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Gleiter, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Wessel, TC
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

De Ryck, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Itri, L
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Prange, H
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Cerami, A
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Brines, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany

Sirén, AL
论文数: 0 引用数: 0
h-index: 0
机构: Univ Gottingen, Max Planck Inst Expt Med, Dept Neurol, D-37075 Gottingen, Germany
[6]
Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke
[J].
Foerch, C
;
Curdt, I
;
Yan, B
;
Dvorak, F
;
Hermans, M
;
Berkefeld, J
;
Raabe, A
;
Neumann-Haefelin, T
;
Steinmetz, H
;
Sitzer, M
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY,
2006, 77 (02)
:181-184

Foerch, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Curdt, I
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Yan, B
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Dvorak, F
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Hermans, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Berkefeld, J
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Raabe, A
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Neumann-Haefelin, T
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Steinmetz, H
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Sitzer, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany
[7]
Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction
[J].
Foerch, C
;
Singer, OC
;
Neumann-Haefelin, T
;
de Rochemont, RDM
;
Steinmetz, H
;
Sitzer, M
.
ARCHIVES OF NEUROLOGY,
2005, 62 (07)
:1130-1134

Foerch, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Singer, OC
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Neumann-Haefelin, T
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

de Rochemont, RDM
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Steinmetz, H
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Sitzer, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany
[8]
Serum S100B predicts a malignant course of infarction in patients with acute middle cerebral artery occlusion
[J].
Foerch, C
;
Otto, B
;
Singer, OC
;
Neumann-Haefelin, T
;
Yan, B
;
Berkefeld, J
;
Steinmetz, H
;
Sitzer, M
.
STROKE,
2004, 35 (09)
:2160-2164

Foerch, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Otto, B
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Singer, OC
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Neumann-Haefelin, T
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Yan, B
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Berkefeld, J
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Steinmetz, H
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany

Sitzer, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Frankfurt, Dept Neurol, D-60528 Frankfurt, Germany
[9]
S100B as a surrogate marker for successful clot lysis in hyperacute middle cerebral artery occlusion
[J].
Foerch, C
;
de Rochemont, RD
;
Singer, O
;
Neumann-Haefelin, T
;
Buchkremer, M
;
Zanella, FE
;
Steinmetz, H
;
Sitzer, M
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY,
2003, 74 (03)
:322-325

Foerch, C
论文数: 0 引用数: 0
h-index: 0

de Rochemont, RD
论文数: 0 引用数: 0
h-index: 0

Singer, O
论文数: 0 引用数: 0
h-index: 0

Neumann-Haefelin, T
论文数: 0 引用数: 0
h-index: 0

Buchkremer, M
论文数: 0 引用数: 0
h-index: 0

Zanella, FE
论文数: 0 引用数: 0
h-index: 0

Steinmetz, H
论文数: 0 引用数: 0
h-index: 0

Sitzer, M
论文数: 0 引用数: 0
h-index: 0
[10]
Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure
[J].
Heo, JH
;
Kim, SH
;
Lee, KY
;
Kim, EH
;
Chu, CK
;
Nam, JM
.
STROKE,
2003, 34 (06)
:E48-E50

Heo, JH
论文数: 0 引用数: 0
h-index: 0
机构: Yonsei Univ, Coll Med, Dept Neurol, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

Kim, SH
论文数: 0 引用数: 0
h-index: 0
机构: Yonsei Univ, Coll Med, Dept Neurol, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

Lee, KY
论文数: 0 引用数: 0
h-index: 0
机构: Yonsei Univ, Coll Med, Dept Neurol, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

Kim, EH
论文数: 0 引用数: 0
h-index: 0
机构: Yonsei Univ, Coll Med, Dept Neurol, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

Chu, CK
论文数: 0 引用数: 0
h-index: 0
机构: Yonsei Univ, Coll Med, Dept Neurol, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

Nam, JM
论文数: 0 引用数: 0
h-index: 0
机构: Yonsei Univ, Coll Med, Dept Neurol, Brain Korea Project Med Sci 21, Seoul 120752, South Korea