Sustainable Synthesis of Flavonoid Derivatives, QSAR Study and Insecticidal Activity against the Fall Armyworm, Spodoptera frugiperda (Lep.: Noctuidae)

被引：41

作者：

Romanelli, Gustavo P. ^{[1
,2
]}

Virla, Eduardo G. ^{[3
]}

Duchowicz, Pablo R. ^{[4
]}

Gaddi, Ana L. ^{[2
]}

Ruiz, Diego M. ^{[1
]}

Bennardi, Daniel O. ^{[1
]}

del Valle Ortiz, Erlinda ^{[5
]}

Autino, Juan C. ^{[1
]}

机构：

[1] Univ Nacl La Plata, Fac Ciencias Agr & Forestales, Catedra Quim Organ, RA-1904 La Plata, Buenos Aires, Argentina

[2] Univ Nacl La Plata, CCT CONICET, Dept Quim,Fac Ciencias Exactas, Ctr Invest & Desarrollo Ciencias Aplicadas Dr Jor, RA-1900 La Plata, Buenos Aires, Argentina

[3] Planta Piloto Proc Ind Microbiol PROIMI, Div Biol Control, RA-4000 San Miguel De Tucuman, Tucuman, Argentina

[4] CCT La Plata CONICET, UNLP, INIFTA, RA-1900 La Plata, Buenos Aires, Argentina

[5] Univ Nacl Catamarca, Fac Tecnol & Ciencias Aplicadas, RA-4700 Catamarca, Argentina

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2010年 / 58卷 / 10期

关键词：

Fall armyworm; flavones; heteropolyacid; Insecticidal activity; Preyssler catalyst; QSAR; Spodoptera frugiperda; sustainable synthesis; ANTIFEEDANT ACTIVITY; REPLACEMENT METHOD; CHROMONES; ESTERIFICATION; LEPIDOPTERA; SELECTION; ROUTE; QSPR;

D O I：

10.1021/jf100073j

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

A simple, clean, solvent-free preparation of flavones by the use of a silica-supported Preyssler heteropolyacid as reusable catalyst is described. High selectivity and very good yields (87-94%) were obtained in short reaction times (7-13 min). Bioassays for insecticidal activity against Spodoptera frugiperda were carried out with a set of flavones. Bioassays showed that some of the flavones had moderate insecticidal activity. Quantitative structure-activity relationships were established on the available data with the purpose of predicting the insecticidal activity of a number of structurally related flavones. A relationship between the molecular structure and biological activity is proposed.

引用

页码：6290 / 6295

页数：6

共 48 条

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