Biodegradable microfluidics

被引:130
作者
King, KR
Wang, CCJ
Kaazempur-Mofrad, MR
Vacanti, JP
Borenstein, JT [1 ]
机构
[1] Charles Stark Draper Lab Inc, Cambridge, MA 02139 USA
[2] MIT, Dept Mech Engn, Cambridge, MA 02139 USA
[3] Harvard Univ, Sch Med, Dept Surg, Boston, MA 02114 USA
[4] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA
关键词
D O I
10.1002/adma.200306522
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A biodegradable microfabrication platform for constructing 3D high-resolution devices for tissue engineering and drug delivery is presented. Biodegradable polymer films with built-in micrometer-scale features are stacked and fusion bonded to construct fully biodegradable, poly(DL-lactic-co-glycolide) (PLGA)-based, monolithic, multilayer, microfluidic networks. Integration with cells or drug compounds will enable use of these devices in therapeutic applications (scale bar: similar to 300 mum).
引用
收藏
页码:2007 / +
页数:7
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