"Beyond MELD" - Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation

被引：40
作者：
Ge, Jin [1 ]
Kim, W. Ray [2 ]
Lai, Jennifer C. [1 ]
Kwong, Allison J. [2 ]
机构：
[1] Univ Calif San Francisco, Dept Med, Div Gastroenterol & Hepatol, San Francisco, CA USA
[2] Stanford Univ, Sch Med, Dept Med, Div Gastroenterol & Hepatol, Stanford, CA USA
来源：
JOURNAL OF HEPATOLOGY | 2022年 / 76卷 / 06期
关键词：
Prognostication; Allocation; Frailty; Sarcopenia; EHR; OMOP; Clinical Decision Support; ARTIFICIAL NEURAL-NETWORKS; ELECTRONIC HEALTH RECORD; DISEASE MELD; BIG DATA; MODEL; CIRRHOSIS; SURVIVAL; FRAILTY; SCORE; GUIDELINES;
D O I：
10.1016/j.jhep.2022.03.003
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
In this review article, we discuss the model for end-stage liver disease (MELD) score and its dual purpose in general and transplant hepatology. As the landscape of liver disease and transplantation has evolved considerably since the advent of the MELD score, we summarise emerging concepts, methodologies, and technologies that may improve mortality prognostication in the future. Finally, we explore how these novel concepts and technologies may be incorporated into clinical practice. (C) 2022 Published by Elsevier B.V. on behalf of European Association for the Study of the Liver.
引用
收藏
页码：1318 / 1329
页数：12
相关论文
共 150 条
[1]   Role and Challenges of Unstructured Big Data in Healthcare [J].
Adnan, Kiran ;
Akbar, Rehan ;
Khor, Siak Wang ;
Ali, Adnan Bin Amanat .
DATA MANAGEMENT, ANALYTICS AND INNOVATION, ICDMAI 2019, VOL 1, 2020, 1042 :301-323
[2]   Reduced Access to Liver Transplantation in Women: Role of Height, MELD Exception Scores, and Renal Function Underestimation [J].
Allen, Alina M. ;
Heimbach, Julie K. ;
Larson, Joseph J. ;
Mara, Kristin C. ;
Kim, W. Ray ;
Kamath, Patrick S. ;
Therneau, Terry M. .
TRANSPLANTATION, 2018, 102 (10) :1710-1716
[3]  
[Anonymous], 1999, Fed Regist, V64, P56650
[4]  
[Anonymous], European health data evidence network
[5]  
[Anonymous], ADOPTION ELECT HLTH
[6]  
[Anonymous], the continuous distribution of entanglement in multiuser
[7]  
[Anonymous], OHDSI - Observational Health Data Sciences and Informatics
[8]  
[Anonymous], WHAT WE BIASES AI
[9]   MELD-GRAIL-Na: Glomerular Filtration Rate and Mortality on Liver-Transplant Waiting List [J].
Asrani, Sumeet K. ;
Jennings, Linda W. ;
Kim, W. R. ;
Kamath, Patrick S. ;
Levitsky, Josh ;
Nadim, Mitra K. ;
Testa, Giuliano ;
Leise, Michael D. ;
Trotter, James F. ;
Klintmalm, Goran .
HEPATOLOGY, 2020, 71 (05) :1766-1774
[10]   A Model for Glomerular Filtration Rate Assessment in Liver Disease (GRAIL) in the Presence of Renal Dysfunction [J].
Asrani, Sumeet K. ;
Jennings, Linda W. ;
Trotter, James F. ;
Levitsky, Josh ;
Nadim, Mitra K. ;
Kim, W. R. ;
Gonzalez, Stevan A. ;
Fischbach, Bernard ;
Bahirwani, Ranjeeta ;
Emmett, Michael ;
Klintmalm, Goran .
HEPATOLOGY, 2019, 69 (03) :1219-1230
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