Prevention of postpartum hemorrhage at home birth in Afghanistan

被引：72

作者：

Sanghvi, Harshadkumar ^{[1
]}

Ansari, Nasratullah ^{[2
]}

Prata, Ndola J. V. ^{[3
]}

Gibson, Hannah ^{[2
]}

Ehsan, Aftab T. ^{[4
]}

Smith, Jeffrey M. ^{[2
]}

机构：

[1] Jhpiego, Baltimore, MD 21231 USA

[2] Jhpiego, Baltimore, Kabul, Afghanistan

[3] Venture Strategies Hlth & Dev, Berkeley, CA USA

[4] Save Children, Kabul, Afghanistan

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2010年 / 108卷 / 03期

关键词：

Afghanistan; Community-based distribution; Maternal mortality; Misoprostol; Postpartum hemorrhage; Skilled attendance; RANDOMIZED CONTROLLED-TRIAL; PLACEBO-CONTROLLED TRIAL; 3RD STAGE; ORAL MISOPROSTOL; LABOR; MANAGEMENT; DEATH;

D O I：

10.1016/j.ijgo.2009.12.003

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective To test the safety, acceptability, feasibility, and effectiveness of community-based education and distribution of misoprostol for prevention of postpartum hemorrhage at home birth in Afghanistan Methods A nonrandomized experimental control design in rural Afghanistan Results A total of 3187 women participated 2039 in the intervention group and 1148 in the control group. Of the 1421 women in the intervention group who took misoprostal. 100% correctly took it after birth, including 20 women with twin pregnancies Adverse effect rates wre unexpectedly lower in the intervention group than in the comparision group Among women in the intervention group. 92% said the would use misoprostol in their next pregnancy. In the intervention area where community-based distribution of misoprostol was introduced, near-universal uterotonic coverage (92%) was achieved compared with 25% coverage in the control areas Conclusion In Afhanistan, community-based education and distribution misoprotol is safe, acceptable, feasible, and effective. This strategy should be considered for other countries where access to skilled attendance is limited. (C) 2009 International Federation of Gynecology and Obstetrics Published by Elsevier Ireland Ltd All rights reserved.

引用

页码：276 / 281

页数：6

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