Endocannabinoid signaling pathways: beyond CB1R and CB2R

被引:22
作者
Biringer, Roger Gregory [1 ]
机构
[1] Lake Erie Coll Osteopath Med, Coll Osteopath Med, Bradenton, FL 34211 USA
关键词
Anandamide; 2-Acyl glycerol; Endocannabinoid; Phytocannabinoid; Cannabinoid; N-ARACHIDONOYL GLYCINE; COUPLED RECEPTOR 18; LYSOPHOSPHATIDIC ACID RECEPTOR; ROSTRAL VENTROLATERAL MEDULLA; GLUCAGON-LIKE PEPTIDE-1; CANNABINOID RECEPTORS; PANCREATIC BETA; HIGH-AFFINITY; CYCLIC-AMP; SPHINGOSINE; 1-PHOSPHATE;
D O I
10.1007/s12079-021-00622-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The search for cannabinoid receptors other than CB1R and CB2R has been ongoing for over a decade. A number of orphan receptors have been proposed as potential cannabinoid receptors primarily based on phylogenic arguments and reactivity towards known endocannabinoids and phytocannabinoids. Seven putative cannabinoid receptors are described and discussed, and evidence for and against their inclusion in this category are presented.
引用
收藏
页码:335 / 360
页数:26
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