Apototic signaling cascades

被引：126
作者：
Ashe, PC [1 ]
Berry, MD [1 ]
机构：
[1] Alviva Biopharmaceut Inc, Saskatoon, SK S7N 3R2, Canada
来源：
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 2003年 / 27卷 / 02期
关键词：
apoptosis; bcl-2; proteins; caspases; death receptor; mitochondria; signal transduction;
D O I：
10.1016/S0278-5846(03)00016-2
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Apoptosis is a form of programmed cell death that results in the orderly and efficient removal of damaged or unnecessary cells, such as those resulting from DNA damage or during development. There are many factors that contribute to this process, each demonstrating specificity of function, regulation, and pathway involvement. The aim of this brief overview is to provide an introduction to a number of these factors as well as the various apoptotic pathways that have been identified. (C) 2003 Elsevier Science Inc. All rights reserved.
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收藏
页码：199 / 214
页数：16
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