Reactivity of 3-iodoimidazo[1,2-a]pyridines using a Suzuki-type cross-coupling reaction

被引：102

作者：

Enguehard, C

Renou, JL

Collot, V

Hervet, M

Rault, S

Gueiffier, A

机构：

[1] UFR Sci Pharmaceut, Chim Therapeut Lab, F-37200 Tours, France

[2] Ctr Etud & Rech Medicament Normandie, UFR Sci Pharmaceut, F-14032 Caen, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 20期

关键词：

D O I：

10.1021/jo000698z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The influence of base and solvent in Suzuki cross-coupling reaction on various 2-substituted-3-iodbimidazo[1,2-a]pyridines was reported. The reactivity was largely influenced by nature of the substituent. Optimized yields and shortened times of reaction were obtained using strong bases in DME.

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页码：6572 / 6575

页数：4

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