Total synthesis of (-)-martinellic acid

被引：38
作者：
Badarinarayana, Vivek [1 ]
Lovely, Carl J. [1 ]
机构：
[1] Univ Texas, Dept Chem & Biochem, Arlington, TX 76019 USA
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 14期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/j.tetlet.2007.02.008
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An enantioselective formal total synthesis of the pyrrolo[3,2-c]quinoline natural product martinellic acid has been achieved. The key steps involve a Pd-catalyzed aryl amidation reaction of a pyrroglutamate derivative, an intramolecular [3+2] azomethine ylide-alkene cycloaddition and a reductive ring opening reaction. (c) 2007 Elsevier Ltd. All rights reserved.
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收藏
页码：2607 / 2610
页数：4
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