Total synthesis of (-)-martinellic acid

被引：38

作者：

Badarinarayana, Vivek ^{[1
]}

Lovely, Carl J. ^{[1
]}

机构：

[1] Univ Texas, Dept Chem & Biochem, Arlington, TX 76019 USA

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 14期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/j.tetlet.2007.02.008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioselective formal total synthesis of the pyrrolo[3,2-c]quinoline natural product martinellic acid has been achieved. The key steps involve a Pd-catalyzed aryl amidation reaction of a pyrroglutamate derivative, an intramolecular [3+2] azomethine ylide-alkene cycloaddition and a reductive ring opening reaction. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：2607 / 2610

页数：4

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