Nanoscaled biocompatible magnetic drug-delivery system: preparation and characterization

被引：6
作者：
Morais, P. C. [1 ]
Garg, V. K. [1 ]
Oliveira, A. C. [1 ]
Silveira, L. B. [2 ]
Santos, J. G. [2 ]
Rodrigues, M. M. A. [3 ]
Tedesco, A. C. [3 ]
机构：
[1] Univ Brasilia, Nucleo Fis Aplicada, Inst Fis, BR-70910900 Brasilia, DF, Brazil
[2] Fundacao Univ Fed Rondonia, Dept Ciencias Exatas Nat Fdn, BR-78961970 Porto Velho, RO, Brazil
[3] Univ Sao Paulo, Fac Filosofia Ciencias & Letras, Dept Quim, Lab Fotobiol & Fotomed, BR-14040901 Ribeirao Preto, SP, Brazil
来源：
ISIAME 2008 | 2009年
关键词：
Biocompatible maghemite nanocomposite; Mossbauer spectroscopy; Bovine serum albumin; Magnetic fluid; MAGHEMITE NANOPARTICLES; MOSSBAUER-SPECTROSCOPY; PARTICLES; PROTEINS; SURFACE; CELLS;
D O I：
10.1007/978-3-642-01369-0_34
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Biocompatible magnetic nanocomposite consisting of bovine serum albumin-based nanosized spheres hosting maghemite nanoparticle has been investigated by Mossbauer spectroscopy, X-ray diffraction, and electron microscopy. The 77 K Mossbauer spectrum was curve-fitted to two sextets whereas one doublet plus one sextet was used to fit the 300 K Mossbauer spectrum. The temperature evolution of the hyperfine parameters indicated two Mossbauer components; one associated to the core maghemite nanoparticle and the other associated to the maghemite surface shell. The 300 K quadrupole splitting value indicated strong interaction between the surface of the maghemite nanoparticle and the hosting template.
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收藏
页码：269 / +
页数：3
相关论文
共 25 条
  • [1] VACANCY DISTRIBUTION IN SYNTHETIC SPINELS OF SERIES FE3O4-GAMMA-FE2O3
    ANNERSTE, H
    HAFNER, SS
    [J]. ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1973, 137 (5-6): : 321 - 340
  • [2] Synthesis, characterization and targeting of biodegradable magnetic nanocomposite particles by external magnetic fields
    Asmatulu, R
    Zalich, MA
    Claus, RO
    Riffle, JS
    [J]. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2005, 292 : 108 - 119
  • [3] Targeting HSP70-induced thermotolerance for design of thermal sensitizers
    Calderwood, SK
    Asea, A
    [J]. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2002, 18 (06) : 597 - 608
  • [4] Cullity B D., 1978, ELEMENTS XRAY DIFFRA, Vsecond ed.
  • [5] Attachment of water-soluble proteins to the surface of (magnetizable) phospholipid colloids via NeutrAvidin-derivatized phospholipids
    De Cuyper, M
    Hodenius, M
    Lacava, ZGM
    Azevedo, RB
    da Silva, MD
    Morais, PC
    Santana, MHA
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2002, 245 (02) : 274 - 280
  • [6] Synthesis of colloidal superparamagnetic nanocomposites by grafting poly(ε-caprolactone) from the surface of organosilane-modified maghemite nanoparticles
    Flesch, C
    Bourgeat-Lami, E
    Mornet, S
    Duguet, E
    Delaite, C
    Dumas, P
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2005, 43 (15) : 3221 - 3231
  • [7] Biocompatible magnetic core/shell nanoparticles
    Goetze, T
    Gansau, C
    Buske, N
    Roeder, M
    Görnert, P
    Bahr, M
    [J]. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2002, 252 (1-3) : 399 - 402
  • [8] Guedes MHA, 2004, J MAGN MAGN MATER, V272, P2406, DOI [10.1016/j.jmmm.2003.12.709, 10.1016/j.j,,,.2003.12.709]
  • [9] Spin-canting and transverse relaxation in maghemite nanoparticles and in tin-doped maghemite
    Helgason, Ö
    Rasmussen, HK
    Morup, S
    [J]. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2006, 302 (02) : 413 - 420
  • [10] Magnetic particle hyperthermia:: nanoparticle magnetism and materials development for cancer therapy
    Hergt, Rudolf
    Dutz, Silvio
    Mueller, Robert
    Zeisberger, Matthias
    [J]. JOURNAL OF PHYSICS-CONDENSED MATTER, 2006, 18 (38) : S2919 - S2934
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